Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2016 1
2017 1
2022 0
Text availability
Article attribute
Article type
Publication date

Search Results

2 results
Results by year
Filters applied: . Clear all
Page 1
Evolution of Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.
Andersson TB. Andersson TB. Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):234-238. doi: 10.1111/bcpt.12804. Epub 2017 Jul 3. Basic Clin Pharmacol Toxicol. 2017. PMID: 28470941 Free article. Review.
Development of in vitro model systems that emulate the functions of the human liver organ has been an elusive task. Cell lines exhibit a low drug-metabolizing capacity and primary liver cells rapidly dedifferentiate in culture, whi …
Development of in vitro model systems that emulate the functions of the human liver organ has been an elusive ta …
Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.
Lauschke VM, Hendriks DF, Bell CC, Andersson TB, Ingelman-Sundberg M. Lauschke VM, et al. Chem Res Toxicol. 2016 Dec 19;29(12):1936-1955. doi: 10.1021/acs.chemrestox.6b00150. Epub 2016 Sep 23. Chem Res Toxicol. 2016. PMID: 27661221 Review.
Hitherto, mainly animal studies and 2D hepatocyte systems have been used for the examination of human drug metabolism and toxicity. ...It is concluded that the development of 3D liver models has hitherto been fruitful and that systems …
Hitherto, mainly animal studies and 2D hepatocyte systems have been used for the examination of human drug metab …