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MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy.
Polak A, Kiliszek P, Sewastianik T, Szydłowski M, Jabłońska E, Białopiotrowicz E, Górniak P, Markowicz S, Nowak E, Grygorowicz MA, Prochorec-Sobieszek M, Nowis D, Gołąb J, Giebel S, Lech-Marańda E, Warzocha K, Juszczyński P. Polak A, et al. Among authors: nowak e. PLoS One. 2016 May 19;11(5):e0155893. doi: 10.1371/journal.pone.0155893. eCollection 2016. PLoS One. 2016. PMID: 27196001 Free PMC article.
FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.
Szydlowski M, Kiliszek P, Sewastianik T, Jablonska E, Bialopiotrowicz E, Gorniak P, Polak A, Markowicz S, Nowak E, Grygorowicz MA, Prochorec-Sobieszek M, Szumera-Cieckiewicz A, Malenda A, Lech-Maranda E, Warzocha K, Juszczynski P. Szydlowski M, et al. Among authors: nowak e. Blood. 2016 Feb 11;127(6):739-48. doi: 10.1182/blood-2015-06-654111. Epub 2015 Nov 19. Blood. 2016. PMID: 26585955 Free article.
FOXO1 is a TXN- and p300-dependent sensor and effector of oxidative stress in diffuse large B-cell lymphomas characterized by increased oxidative metabolism.
Sewastianik T, Szydlowski M, Jablonska E, Bialopiotrowicz E, Kiliszek P, Gorniak P, Polak A, Prochorec-Sobieszek M, Szumera-Cieckiewicz A, Kaminski TS, Markowicz S, Nowak E, Grygorowicz MA, Warzocha K, Juszczynski P. Sewastianik T, et al. Among authors: nowak e. Oncogene. 2016 Nov 17;35(46):5989-6000. doi: 10.1038/onc.2016.126. Epub 2016 May 2. Oncogene. 2016. PMID: 27132507
Human regulatory T cells suppress proliferation of B lymphoma cells.
Grygorowicz MA, Biernacka M, Bujko M, Nowak E, Rymkiewicz G, Paszkiewicz-Kozik E, Borycka IS, Bystydzienski Z, Walewski J, Markowicz S. Grygorowicz MA, et al. Among authors: nowak e. Leuk Lymphoma. 2016 Aug;57(8):1903-20. doi: 10.3109/10428194.2015.1121260. Epub 2016 Jan 12. Leuk Lymphoma. 2016. PMID: 26758248
A retinoic acid-dependent checkpoint in the development of CD4+ T cell-mediated immunity.
Pino-Lagos K, Guo Y, Brown C, Alexander MP, Elgueta R, Bennett KA, De Vries V, Nowak E, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Noelle RJ. Pino-Lagos K, et al. Among authors: nowak e. J Exp Med. 2011 Aug 29;208(9):1767-75. doi: 10.1084/jem.20102358. Epub 2011 Aug 22. J Exp Med. 2011. PMID: 21859847 Free PMC article.
IL-9 as a mediator of Th17-driven inflammatory disease.
Nowak EC, Weaver CT, Turner H, Begum-Haque S, Becher B, Schreiner B, Coyle AJ, Kasper LH, Noelle RJ. Nowak EC, et al. J Exp Med. 2009 Aug 3;206(8):1653-60. doi: 10.1084/jem.20090246. Epub 2009 Jul 13. J Exp Med. 2009. PMID: 19596803 Free PMC article.
397 results