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2004 8
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2020 0
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Page 1
Thermally cross-linked superparamagnetic iron oxide nanoparticle-A10 RNA aptamer-doxorubicin conjugate.
Zhang H. Zhang H. 2008 Aug 29 [updated 2008 Oct 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. Molecular Imaging and Contrast Agent Database (MICAD). 2004–2013. PMID: 20641568 Free Books & Documents. Review.
PSMA is composed of several domains, including a potential phosphorylation site in the cytoplasmic tail (amino acids 1–18), a highly hydrophobic α-helix in the transmembrane region (amino acids 19–43), and catalytic sites in the extensive extracellular domain (amino …
PSMA is composed of several domains, including a potential phosphorylation site in the cytoplasmic tail (amino acids 1–18), a highly …
Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines.
Patel M, Agarwal R, Ardalan B. Patel M, et al. J Cancer Res Clin Oncol. 2004 Aug;130(8):453-9. doi: 10.1007/s00432-004-0575-6. Epub 2004 Jun 15. J Cancer Res Clin Oncol. 2004. PMID: 15205948
METHODS: HT-29 cells were exposed for 2 h to IC(10), IC(30), and IC(70) of oxaliplatin and CPT-11. Subsequently, cells were exposed for 24 h to IC(10), IC(30), and IC(70) of 5-FU, FUdR, and FUR. ...RESULTS: Synergistic cytotoxicity was displayed when IC(30) of oxali …
METHODS: HT-29 cells were exposed for 2 h to IC(10), IC(30), and IC(70) of oxaliplatin and CPT-11. Subsequently, cells were exposed f …
5'-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation.
Wang XQ, Rothnagel JA. Wang XQ, et al. Nucleic Acids Res. 2004 Feb 27;32(4):1382-91. doi: 10.1093/nar/gkh305. Print 2004. Nucleic Acids Res. 2004. PMID: 14990743 Free PMC article.
Moreover, approximately 10% of ribosomes exhibited leaky scanning at uAUGs in the most favourable context and initiated at a downstream AUG. ...We found significant levels of initiation at the main ORF even in constructs containing four uORFs, with nearly 10% …
Moreover, approximately 10% of ribosomes exhibited leaky scanning at uAUGs in the most favourable context and initiated at a downstre …
Gram-positive anaerobic bacilli in human periodontal disease.
Booth V, Downes J, Van den Berg J, Wade WG. Booth V, et al. J Periodontal Res. 2004 Aug;39(4):213-20. doi: 10.1111/j.1600-0765.2004.00726.x. J Periodontal Res. 2004. PMID: 15206913
Oligonucleotide probes were designed for Bulleidia extructa, Eubacterium nodatum, Mogibacterium timidum and Slackia exigua and used to probe nucleic acids extracted from the samples with a chemiluminescent detection method. Species were quantified as absent or prese …
Oligonucleotide probes were designed for Bulleidia extructa, Eubacterium nodatum, Mogibacterium timidum and Slackia exigua and used to probe …
Submicron patterning of DNA oligonucleotides on silicon.
Yin HB, Brown T, Wilkinson JS, Eason RW, Melvin T. Yin HB, et al. Nucleic Acids Res. 2004 Aug 16;32(14):e118. doi: 10.1093/nar/gnh113. Nucleic Acids Res. 2004. PMID: 15314186 Free PMC article.
Complementary oligonucleotides were hybridized to the surface-attached oligonucleotides with a density of 7 x 10(12) DNA oligonucleotides per square centimetre. ...
Complementary oligonucleotides were hybridized to the surface-attached oligonucleotides with a density of 7 x 10(12) DNA oligonucleot …
Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding.
Lam AM, Rypma RS, Frick DN. Lam AM, et al. Nucleic Acids Res. 2004 Aug 2;32(13):4060-70. doi: 10.1093/nar/gkh743. Print 2004. Nucleic Acids Res. 2004. PMID: 15289579 Free PMC article.
All proteins unwound RNA and DNA best at pH 6.5, which demonstrate that conserved NS3 helicase domain amino acids are responsible for low-pH enzyme activation. ...Both the turnover rate of ATP hydrolysis and the K(m) of ATP were similar between pH 6 and 10, but the …
All proteins unwound RNA and DNA best at pH 6.5, which demonstrate that conserved NS3 helicase domain amino acids are responsible for …
AdoMet radical proteins--from structure to evolution--alignment of divergent protein sequences reveals strong secondary structure element conservation.
Nicolet Y, Drennan CL. Nicolet Y, et al. Nucleic Acids Res. 2004 Aug 2;32(13):4015-25. doi: 10.1093/nar/gkh728. Print 2004. Nucleic Acids Res. 2004. PMID: 15289575 Free PMC article.
These differences in barrel architecture also explain how AdoMet radical enzymes can act on substrates that range in size from 10 atoms to 608 residue proteins....
These differences in barrel architecture also explain how AdoMet radical enzymes can act on substrates that range in size from 10 ato …
Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles.
Wu Y, de Kievit P, Vahlkamp L, Pijnenburg D, Smit M, Dankers M, Melchers D, Stax M, Boender PJ, Ingham C, Bastiaensen N, de Wijn R, van Alewijk D, van Damme H, Raap AK, Chan AB, van Beuningen R. Wu Y, et al. Nucleic Acids Res. 2004 Aug 27;32(15):e123. doi: 10.1093/nar/gnh118. Nucleic Acids Res. 2004. PMID: 15333674 Free PMC article.
Additionally, the system demonstrates a linear dynamic range of 3 orders of magnitude and at least 10-fold decreased hybridization time compared to conventional microarrays. ...
Additionally, the system demonstrates a linear dynamic range of 3 orders of magnitude and at least 10-fold decreased hybridization ti …
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