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RNA polymerase: the vehicle of transcription.
Borukhov S, Nudler E. Borukhov S, et al. Trends Microbiol. 2008 Mar;16(3):126-34. doi: 10.1016/j.tim.2007.12.006. Epub 2008 Feb 14. Trends Microbiol. 2008. PMID: 18280161 Review.
Coupling between transcription termination and RNA polymerase inchworming.
Nudler E, Kashlev M, Nikiforov V, Goldfarb A. Nudler E, et al. Cell. 1995 May 5;81(3):351-7. doi: 10.1016/0092-8674(95)90388-7. Cell. 1995. PMID: 7736587
Advancement of RNA polymerase of E. coli occurs in alternating laps of monotonic and inchworm-like movement. Cycles of inchworming are encoded in DNA and involve straining and relaxation of the ternary complex accompanied by characteristic leaping of DNA and RNA footprints …
Advancement of RNA polymerase of E. coli occurs in alternating laps of monotonic and inchworm-like movement. Cycles of inchworming ar …
Discontinuous mechanism of transcription elongation.
Nudler E, Goldfarb A, Kashlev M. Nudler E, et al. Science. 1994 Aug 5;265(5173):793-6. doi: 10.1126/science.8047884. Science. 1994. PMID: 8047884
Histidine-tagged RNA polymerase of Escherichia coli and transcription in solid phase.
Kashlev M, Nudler E, Severinov K, Borukhov S, Komissarova N, Goldfarb A. Kashlev M, et al. Methods Enzymol. 1996;274:326-34. doi: 10.1016/s0076-6879(96)74028-4. Methods Enzymol. 1996. PMID: 8902816 No abstract available.
The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase.
Nudler E, Mustaev A, Lukhtanov E, Goldfarb A. Nudler E, et al. Cell. 1997 Apr 4;89(1):33-41. doi: 10.1016/s0092-8674(00)80180-4. Cell. 1997. PMID: 9094712
An 8-9 bp RNA-DNA hybrid in the transcription elongation complex is essential for keeping the RNA 3' terminus engaged with the active site of E. coli RNA polymerase (RNAP). ...
An 8-9 bp RNA-DNA hybrid in the transcription elongation complex is essential for keeping the RNA 3' terminus engaged with the active site o …
Spatial organization of transcription elongation complex in Escherichia coli.
Nudler E, Gusarov I, Avetissova E, Kozlov M, Goldfarb A. Nudler E, et al. Science. 1998 Jul 17;281(5375):424-8. doi: 10.1126/science.281.5375.424. Science. 1998. PMID: 9665887
The mechanism of intrinsic transcription termination.
Gusarov I, Nudler E. Gusarov I, et al. Mol Cell. 1999 Apr;3(4):495-504. doi: 10.1016/s1097-2765(00)80477-3. Mol Cell. 1999. PMID: 10230402
Transcription elongation: structural basis and mechanisms.
Nudler E. Nudler E. J Mol Biol. 1999 Apr 23;288(1):1-12. doi: 10.1006/jmbi.1999.2641. J Mol Biol. 1999. PMID: 10329121 Review.
Mechanistic model of the elongation complex of Escherichia coli RNA polymerase.
Korzheva N, Mustaev A, Nudler E, Nikiforov V, Goldfarb A. Korzheva N, et al. Cold Spring Harb Symp Quant Biol. 1998;63:337-45. doi: 10.1101/sqb.1998.63.337. Cold Spring Harb Symp Quant Biol. 1998. PMID: 10384298 No abstract available.
Isolation and characterization of sigma(70)-retaining transcription elongation complexes from Escherichia coli.
Bar-Nahum G, Nudler E. Bar-Nahum G, et al. Cell. 2001 Aug 24;106(4):443-51. doi: 10.1016/s0092-8674(01)00461-5. Cell. 2001. PMID: 11525730
Here, we identify a population of RNAP from E. coli that retains sigma(70) throughout elongation. The relative amount of this population appears to depend on cellular growth and reaches its maximum during the stationary phase. ...
Here, we identify a population of RNAP from E. coli that retains sigma(70) throughout elongation. The relative amount of this populat …
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