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Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex.
Chiba S, Numakawa T, Ninomiya M, Richards MC, Wakabayashi C, Kunugi H. Chiba S, et al. Among authors: numakawa t. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Oct 1;39(1):112-9. doi: 10.1016/j.pnpbp.2012.05.018. Epub 2012 Jun 1. Prog Neuropsychopharmacol Biol Psychiatry. 2012. PMID: 22664354
Impact of glucocorticoid on neurogenesis.
Odaka H, Adachi N, Numakawa T. Odaka H, et al. Among authors: numakawa t. Neural Regen Res. 2017 Jul;12(7):1028-1035. doi: 10.4103/1673-5374.211174. Neural Regen Res. 2017. PMID: 28852377 Free PMC article. Review.
83 results