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Pharmacokinetic-pharmacodynamic interaction between nebicapone and controlled-release levodopa/benserazide: a single-center, Phase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects.
Nunes T, Machado R, Rocha JF, Fernandes-Lopes C, Costa R, Torrão L, Loureiro AI, Falcão A, Vaz-da-Silva M, Wright L, Almeida L, Soares-da-Silva P. Nunes T, et al. Clin Ther. 2009 Oct;31(10):2258-71. doi: 10.1016/j.clinthera.2009.10.019. Clin Ther. 2009. PMID: 19922897 Clinical Trial.
Effect of opicapone multiple-dose regimens on levodopa pharmacokinetics.
Rocha JF, Sicard É, Fauchoux N, Falcão A, Santos A, Loureiro AI, Pinto R, Bonifácio MJ, Nunes T, Almeida L, Soares-da-Silva P. Rocha JF, et al. Among authors: nunes t. Br J Clin Pharmacol. 2017 Mar;83(3):540-553. doi: 10.1111/bcp.13156. Epub 2016 Dec 2. Br J Clin Pharmacol. 2017. PMID: 27763682 Free PMC article. Clinical Trial.
Evaluation of opicapone on cardiac repolarization in a thorough QT/QTc study.
Pinto R, l'Hostis P, Patat A, Homery MC, Falcão A, Nunes T, Rocha JF, Soares-da-Silva P. Pinto R, et al. Among authors: nunes t. Clin Pharmacol Drug Dev. 2015 Nov;4(6):454-62. doi: 10.1002/cpdd.188. Epub 2015 May 7. Clin Pharmacol Drug Dev. 2015. PMID: 27137718 Clinical Trial.
Effect of moderate liver impairment on the pharmacokinetics of opicapone.
Rocha JF, Santos A, Falcão A, Lopes N, Nunes T, Pinto R, Soares-da-Silva P. Rocha JF, et al. Among authors: nunes t. Eur J Clin Pharmacol. 2014 Mar;70(3):279-86. doi: 10.1007/s00228-013-1602-9. Epub 2013 Nov 24. Eur J Clin Pharmacol. 2014. PMID: 24271646 Clinical Trial.
451 results