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A backup DNA repair pathway moves to the forefront.
Nussenzweig A, Nussenzweig MC. Nussenzweig A, et al. Among authors: nussenzweig mc. Cell. 2007 Oct 19;131(2):223-5. doi: 10.1016/j.cell.2007.10.005. Cell. 2007. PMID: 17956720 Free article.
In vitro V(D)J recombination: signal joint formation.
Cortes P, Weis-Garcia F, Misulovin Z, Nussenzweig A, Lai JS, Li G, Nussenzweig MC, Baltimore D. Cortes P, et al. Among authors: nussenzweig a, nussenzweig mc. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14008-13. doi: 10.1073/pnas.93.24.14008. Proc Natl Acad Sci U S A. 1996. PMID: 8943051 Free PMC article.
Ku80 is required for immunoglobulin isotype switching.
Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H, Qin XF, Besmer E, Kenter A, Rajewsky K, Nussenzweig MC. Casellas R, et al. Among authors: nussenzweig a, nussenzweig mc. EMBO J. 1998 Apr 15;17(8):2404-11. doi: 10.1093/emboj/17.8.2404. EMBO J. 1998. PMID: 9545251 Free PMC article.
Secondary V(D)J recombination in B-1 cells.
Qin XF, Schwers S, Yu W, Papavasiliou F, Suh H, Nussenzweig A, Rajewsky K, Nussenzweig MC. Qin XF, et al. Among authors: nussenzweig a, nussenzweig mc. Nature. 1999 Jan 28;397(6717):355-9. doi: 10.1038/16933. Nature. 1999. PMID: 9950428
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.
Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsuk M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A. Petersen S, et al. Among authors: nussenzweig a, nussenzweig mc. Nature. 2001 Dec 6;414(6864):660-665. doi: 10.1038/414660a. Nature. 2001. PMID: 11740565 Free PMC article.
Genomic instability in mice lacking histone H2AX.
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A. Celeste A, et al. Among authors: nussenzweig a, nussenzweig mc. Science. 2002 May 3;296(5569):922-7. doi: 10.1126/science.1069398. Epub 2002 Apr 4. Science. 2002. PMID: 11934988 Free PMC article.
229 results