Nutt RF - Search Results

1

Guanylpiperidine peptidomimetics: potent and selective bis-cation inhibitors of factor Xa.

Tamura SY, Levy OE, Uong TH, Reiner JE, Goldman EA, Ho JZ, Cohen CR, Bergum PW, Nutt RF, Brunck TK, Semple JE. Tamura SY, et al. Among authors: nutt rf. Bioorg Med Chem Lett. 2000 Apr 17;10(8):745-9. doi: 10.1016/s0960-894x(00)00105-0. Bioorg Med Chem Lett. 2000. PMID: 10782677

2

Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1.

Levy OE, Semple JE, Lim ML, Reiner J, Rote WE, Dempsey E, Richard BM, Zhang E, Tulinsky A, Ripka WC, Nutt RF. Levy OE, et al. Among authors: nutt rf. J Med Chem. 1996 Nov 8;39(23):4527-30. doi: 10.1021/jm960607j. J Med Chem. 1996. PMID: 8917638 No abstract available.

3

Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties.

Semple JE, Rowley DC, Brunck TK, Ha-Uong T, Minami NK, Owens TD, Tamura SY, Goldman EA, Siev DV, Ardecky RJ, Carpenter SH, Ge Y, Richard BM, Nolan TG, Håkanson K, Tulinsky A, Nutt RF, Ripka WC. Semple JE, et al. Among authors: nutt rf. J Med Chem. 1996 Nov 8;39(23):4531-6. doi: 10.1021/jm960572n. J Med Chem. 1996. PMID: 8917639 No abstract available.

4

Investigation of the S3 site of thrombin: design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P1-argininals.

Reiner JE, Lim-Wilby MS, Brunck TK, Ha-Uong T, Goldman EA, Abelman MA, Nutt RF, Semple JE, Tamura SY. Reiner JE, et al. Among authors: nutt rf. Bioorg Med Chem Lett. 1999 Mar 22;9(6):895-900. doi: 10.1016/s0960-894x(99)00102-x. Bioorg Med Chem Lett. 1999. PMID: 10206557

5

Data analysis of high-throughput screening results: application of multidomain clustering to the NCI anti-HIV data set.

Tamura SY, Bacha PA, Gruver HS, Nutt RF. Tamura SY, et al. Among authors: nutt rf. J Med Chem. 2002 Jul 4;45(14):3082-93. doi: 10.1021/jm010535i. J Med Chem. 2002. PMID: 12086494

6

Analysis of large screening data sets via adaptively grown phylogenetic-like trees.

Nicolaou CA, Tamura SY, Kelley BP, Bassett SI, Nutt RF. Nicolaou CA, et al. Among authors: nutt rf. J Chem Inf Comput Sci. 2002 Sep-Oct;42(5):1069-79. doi: 10.1021/ci010244i. J Chem Inf Comput Sci. 2002. PMID: 12376993

7

Development of a potent thrombin receptor ligand.

Feng DM, Veber DF, Connolly TM, Condra C, Tang MJ, Nutt RF. Feng DM, et al. Among authors: nutt rf. J Med Chem. 1995 Sep 29;38(20):4125-30. doi: 10.1021/jm00020a029. J Med Chem. 1995. PMID: 7562949

8

Rule extraction from a mutagenicity data set using adaptively grown phylogenetic-like trees.

Bacha PA, Gruver HS, Den Hartog BK, Tamura SY, Nutt RF. Bacha PA, et al. Among authors: nutt rf. J Chem Inf Comput Sci. 2002 Sep-Oct;42(5):1104-11. doi: 10.1021/ci020366q. J Chem Inf Comput Sci. 2002. PMID: 12376997

9

Quantitation of an orally available thrombin inhibitor in rat, monkey and human plasma and in human urine by high-performance liquid chromatography and fluorescent post-column derivatization of arginine.

Mendoza CB, Dixon SA, Lods MM, Ma MG, Nguyen KT, Nutt RF, Tran HS, Nolan TG. Mendoza CB, et al. Among authors: nutt rf. J Chromatogr A. 1997 Feb 21;762(1-2):299-310. doi: 10.1016/s0021-9673(96)00865-5. J Chromatogr A. 1997. PMID: 9098989

10

The solution conformation of Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist.

Bogusky MJ, Naylor AM, Mertzman ME, Pitzenberger SM, Nutt RF, Brady SF, Colton CD, Veber DF. Bogusky MJ, et al. Among authors: nutt rf. Biopolymers. 1993 Aug;33(8):1287-97. doi: 10.1002/bip.360330813. Biopolymers. 1993. PMID: 8364159

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