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24 results
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Melanocortin overexpression limits diet-induced inflammation and atherosclerosis in LDLR-/- mice.
Nuutinen S, Ailanen L, Savontaus E, Rinne P. Nuutinen S, et al. J Endocrinol. 2018 Mar;236(3):111-123. doi: 10.1530/JOE-17-0636. Epub 2018 Jan 9. J Endocrinol. 2018. PMID: 29317531
Pharmacological activation of the melanocortin system limits plaque inflammation and ameliorates vascular dysfunction in atherosclerotic mice.
Rinne P, Silvola JM, Hellberg S, Ståhle M, Liljenbäck H, Salomäki H, Koskinen E, Nuutinen S, Saukko P, Knuuti J, Saraste A, Roivainen A, Savontaus E. Rinne P, et al. Among authors: nuutinen s. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1346-54. doi: 10.1161/ATVBAHA.113.302963. Epub 2014 May 1. Arterioscler Thromb Vasc Biol. 2014. PMID: 24790139
Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans.
Rinne P, Ahola-Olli A, Nuutinen S, Koskinen E, Kaipio K, Eerola K, Juonala M, Kähönen M, Lehtimäki T, Raitakari OT, Savontaus E. Rinne P, et al. Among authors: nuutinen s. Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1678-86. doi: 10.1161/ATVBAHA.114.305064. Epub 2015 Apr 30. Arterioscler Thromb Vasc Biol. 2015. PMID: 25931512
Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages.
Rinne P, Rami M, Nuutinen S, Santovito D, van der Vorst EPC, Guillamat-Prats R, Lyytikäinen LP, Raitoharju E, Oksala N, Ring L, Cai M, Hruby VJ, Lehtimäki T, Weber C, Steffens S. Rinne P, et al. Among authors: nuutinen s. Circulation. 2017 Jul 4;136(1):83-97. doi: 10.1161/CIRCULATIONAHA.116.025889. Epub 2017 Apr 27. Circulation. 2017. PMID: 28450348 Free PMC article.
Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E-/- Mice.
Rinne P, Kadiri JJ, Velasco-Delgado M, Nuutinen S, Viitala M, Hollmén M, Rami M, Savontaus E, Steffens S. Rinne P, et al. Among authors: nuutinen s. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):313-323. doi: 10.1161/ATVBAHA.117.310418. Epub 2017 Dec 28. Arterioscler Thromb Vasc Biol. 2018. PMID: 29284608 Free PMC article.
Evaluation of the Effect of Fingolimod Treatment on Microglial Activation Using Serial PET Imaging in Multiple Sclerosis.
Sucksdorff M, Rissanen E, Tuisku J, Nuutinen S, Paavilainen T, Rokka J, Rinne J, Airas L. Sucksdorff M, et al. Among authors: nuutinen s. J Nucl Med. 2017 Oct;58(10):1646-1651. doi: 10.2967/jnumed.116.183020. Epub 2017 Mar 23. J Nucl Med. 2017. PMID: 28336784 Free article.
Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress.
van Engeland NCA, Suarez Rodriguez F, Rivero-Müller A, Ristori T, Duran CL, Stassen OMJA, Antfolk D, Driessen RCH, Ruohonen S, Ruohonen ST, Nuutinen S, Savontaus E, Loerakker S, Bayless KJ, Sjöqvist M, Bouten CVC, Eriksson JE, Sahlgren CM. van Engeland NCA, et al. Among authors: nuutinen s. Sci Rep. 2019 Aug 27;9(1):12415. doi: 10.1038/s41598-019-48218-w. Sci Rep. 2019. PMID: 31455807 Free PMC article.
Histamine H3 Receptor Regulates Sensorimotor Gating and Dopaminergic Signaling in the Striatum.
Kononoff Vanhanen J, Nuutinen S, Tuominen M, Panula P. Kononoff Vanhanen J, et al. Among authors: nuutinen s. J Pharmacol Exp Ther. 2016 May;357(2):264-72. doi: 10.1124/jpet.115.230771. Epub 2016 Mar 4. J Pharmacol Exp Ther. 2016. PMID: 26945087
Different Hypothalamic Nicotinic α7 Receptor Expression and Response to Low Nicotine Dose in Alcohol-Preferring and Alcohol-Avoiding Rats.
Nuutinen S, Panula P, Salminen O. Nuutinen S, et al. Alcohol Clin Exp Res. 2016 Feb;40(2):329-34. doi: 10.1111/acer.12960. Alcohol Clin Exp Res. 2016. PMID: 26842251
Histamine H3 receptor antagonist decreases cue-induced alcohol reinstatement in mice.
Nuutinen S, Mäki T, Rozov S, Bäckström P, Hyytiä P, Piepponen P, Panula P. Nuutinen S, et al. Neuropharmacology. 2016 Jul;106:156-63. doi: 10.1016/j.neuropharm.2015.06.006. Epub 2015 Jun 21. Neuropharmacology. 2016. PMID: 26107118
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