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The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A. Bultynck G, et al. Among authors: nuyts k. J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22128171 Free PMC article.
Total synthesis of Septocylindrin B and C-terminus modified analogues.
Nelissen J, Nuyts K, De Zotti M, Lavigne R, Lamberigts C, De Borggraeve WM. Nelissen J, et al. Among authors: nuyts k. PLoS One. 2012;7(12):e51708. doi: 10.1371/journal.pone.0051708. Epub 2012 Dec 20. PLoS One. 2012. PMID: 23284749 Free PMC article.
The zeamine antibiotics affect the integrity of bacterial membranes.
Masschelein J, Clauwers C, Stalmans K, Nuyts K, De Borggraeve W, Briers Y, Aertsen A, Michiels CW, Lavigne R. Masschelein J, et al. Among authors: nuyts k. Appl Environ Microbiol. 2015 Feb;81(3):1139-46. doi: 10.1128/AEM.03146-14. Epub 2014 Dec 1. Appl Environ Microbiol. 2015. PMID: 25452285 Free PMC article.