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Page 1
Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists.
M Ro Rsted E, Jensen AA, Smits G, Frydenvang K, Kristensen JL. M Ro Rsted E, et al. J Med Chem. 2024 Apr 22. doi: 10.1021/acs.jmedchem.4c00082. Online ahead of print. J Med Chem. 2024. PMID: 38648420
These compounds are characterized by broad pharmacological activity profiles, and while the acute mind-altering effects can be ascribed to their shared agonist activity at the serotonin 2A receptor (5-HT(2A)R), their apparent persistent therapeutic effects are yet to be de …
These compounds are characterized by broad pharmacological activity profiles, and while the acute mind-altering effects can be ascribed to t …
Construction of phase-separated Co/MnO synergistic catalysts and integration onto sponge for rapid removal of multiple contaminants.
Liu M, Zhang W, Ni R, Wang Z, Zhao H, Zhong X, Wang Y, Shang D, Guo Z, Ang EH, Yang F. Liu M, et al. Mater Horiz. 2024 Apr 22. doi: 10.1039/d4mh00285g. Online ahead of print. Mater Horiz. 2024. PMID: 38647668
The optimized MnO@Co/C-600 exhibits superior PMS activation efficiency for bisphenol A degradation (0.463 min(-1)), displaying nearly a 20-fold enhancement in the rate constant compared to Mn(3)O(4)/C-600. Subsequent experiments involving variable modulation and extension …
The optimized MnO@Co/C-600 exhibits superior PMS activation efficiency for bisphenol A degradation (0.463 min(-1)), displaying nearly a 20-f …
Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Shen Q, Tang X, Wen X, Cheng S, Xiao P, Zang SK, Shen DD, Jiang L, Zheng Y, Zhang H, Xu H, Mao C, Zhang M, Hu W, Sun JP, Zhang Y, Chen Z. Shen Q, et al. Adv Sci (Weinh). 2024 Apr 22:e2310120. doi: 10.1002/advs.202310120. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38647423
However, the conformational basis of selective coupling of primary G-protein remains elusive. Histamine receptors H(2)R and H(3)R couple with G(s)- or G(i)-proteins respectively. Here, three cryo-EM structures of H(2)R-G(s) and H(3)R-G(i) complexes are …
However, the conformational basis of selective coupling of primary G-protein remains elusive. Histamine receptors H(2)R and H(3)R …
Facile Lithium Densification Kinetics by Hyperporous/Hybrid Conductor for High-Energy-Density Lithium Metal Batteries.
Han DY, Kim S, Nam S, Lee G, Bae H, Kim JH, Choi NS, Song G, Park S. Han DY, et al. Adv Sci (Weinh). 2024 Apr 22:e2402156. doi: 10.1002/advs.202402156. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38647410
Thus, the HCA/C demonstrates stable cycling for 200 cycles with a low negative/positive ratio of 1.0 when paired with a LiNi(0.8)Co(0.1)Mn(0.1)O(2) cathode (areal capacity of 5.0 mAh cm(-2)). Furthermore, a stacked pouch-type full cell using HCA/C realizes a high energy de …
Thus, the HCA/C demonstrates stable cycling for 200 cycles with a low negative/positive ratio of 1.0 when paired with a LiNi(0.8)Co(0.1)Mn(0 …
Cascade Reactions Catalyzed by Gold Hybrid Nanoparticles Generate CO Gas Against Periodontitis in Diabetes.
Wang Y, Chu T, Jin T, Xu S, Zheng C, Huang J, Li S, Wu L, Shen J, Cai X, Deng H. Wang Y, et al. Adv Sci (Weinh). 2024 Apr 22:e2308587. doi: 10.1002/advs.202308587. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38647388
The Glucose-like oxidase activity of Au NPs catalyzes the oxidation of glucose to hydrogen peroxide (H(2)O(2)) and gluconic acid,and then converts H(2)O(2) to hydroxyl radicals (OH) by peroxidase-like activity to destroy bacteria. Moreover, CO production in response …
The Glucose-like oxidase activity of Au NPs catalyzes the oxidation of glucose to hydrogen peroxide (H(2)O(2)) and gluconic acid,and …
Respiration and growth of Paracoccus denitrificans R-1 with nitrous oxide as an electron acceptor.
Zhou J, Deng W, Wu J, Xiang H, Shen X, Lin J-G, Hong Y. Zhou J, et al. Microbiol Spectr. 2024 Apr 22:e0381123. doi: 10.1128/spectrum.03811-23. Online ahead of print. Microbiol Spectr. 2024. PMID: 38647341
These findings suggest that modular N(2)O reduction of P. denitrificans R-1 is linked to the electron transport and energy conservation, and dissimilatory N(2)O reduction is a form of microbial anaerobic respiration. ...Here, we investigated the ability to ob …
These findings suggest that modular N(2)O reduction of P. denitrificans R-1 is linked to the electron transport and energy con …
Rescuing a Troubled Tolcapone with PEGylated PLGA Nanoparticles: Design, Characterization, and Hepatotoxicity Evaluation.
Pinto M, Machado CS, Barreiro S, Otero-Espinar FJ, Remião F, Borges F, Fernandes C. Pinto M, et al. ACS Appl Mater Interfaces. 2024 Apr 22. doi: 10.1021/acsami.4c00614. Online ahead of print. ACS Appl Mater Interfaces. 2024. PMID: 38647198
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor used as adjuvant therapy in Parkinson's disease. ...
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor used as adjuvant therapy in Parkinson's disease. ...
Effects of Internal Stress and Hydrogen Penetration on the Performance of Er(2)O(3) Coatings as Hydrogen Permeation Barriers.
Zheng Z, Yang Z, Yan Y, Wang X, Li H. Zheng Z, et al. ACS Appl Mater Interfaces. 2024 Apr 22. doi: 10.1021/acsami.4c00522. Online ahead of print. ACS Appl Mater Interfaces. 2024. PMID: 38647074
The internal stress was controlled by designing layered Er(2)O(3) coatings. The internal stress increased with an increasing number of Er(2)O(3) layers. ...In addition, the experimental observations and simulation results revealed that the performance of the Er(2) …
The internal stress was controlled by designing layered Er(2)O(3) coatings. The internal stress increased with an increasing number o …
Magneto-optical Properties of Chiral Co2Ln and Co3Ln2 (Ln = Dy and Er) Clusters.
Aibibula M, Song YH, Xu H, Chen MT, Kong XJ, Long LS, Zheng LS. Aibibula M, et al. Inorg Chem. 2024 Apr 22. doi: 10.1021/acs.inorgchem.4c00546. Online ahead of print. Inorg Chem. 2024. PMID: 38647013
A series of chiral heterometallic Ln-Co clusters, denoted as Co(2)Ln and Co(3)Ln(2) (Ln = Dy and Er), were synthesized by reacting the chiral chelating ligand (R/S)-2-(1-hydroxyethyl)pyridine (Hmpm), CoAc(2).4H(2)O, and Ln(NO(3))(3).6H(2)O. ...
A series of chiral heterometallic Ln-Co clusters, denoted as Co(2)Ln and Co(3)Ln(2) (Ln = Dy and Er), were synthesized by reacting the chira …
Effects of Cu(2)O nanoparticles on the kinetic characteristics of rapid chlorophyll fluorescence induction and related genes in wheat seedlings.
Guo W, Wang N, Zhang KY, Song PP, Ma ZQ. Guo W, et al. Ying Yong Sheng Tai Xue Bao. 2024 Mar 18;35(3):721-730. doi: 10.13287/j.1001-9332.202403.009. Ying Yong Sheng Tai Xue Bao. 2024. PMID: 38646760 English.
Investigating the effects of cuprous oxide nanoparticles (Cu(2)O-NPs) on photosystem (PS) of wheat seedling leaves holds considerable importance in comprehending the implications of Cu(2)O-NPs on crop photosynthesis. ...Moreover, there was a decrease in photosynthet …
Investigating the effects of cuprous oxide nanoparticles (Cu(2)O-NPs) on photosystem (PS) of wheat seedling leaves holds considerable …
124,160 results
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