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Page 1
Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT(2A) Receptor Agonists.
M Ro Rsted E, Jensen AA, Smits G, Frydenvang K, Kristensen JL. M Ro Rsted E, et al. J Med Chem. 2024 Apr 22. doi: 10.1021/acs.jmedchem.4c00082. Online ahead of print. J Med Chem. 2024. PMID: 38648420
These compounds are characterized by broad pharmacological activity profiles, and while the acute mind-altering effects can be ascribed to their shared agonist activity at the serotonin 2A receptor (5-HT(2A)R), their apparent persistent therapeutic effects are yet to be de …
These compounds are characterized by broad pharmacological activity profiles, and while the acute mind-altering effects can be ascribed to t …
Enhanced redox kinetics in hierarchical tubular FeSe2 by incorporating Se quantum dots towards high-performance sodium-ion batteries.
Fan H, Yang Z, Cheng Z, Bahmani F, Zhang J, Wu XL. Fan H, et al. J Colloid Interface Sci. 2024 Apr 14;667:303-311. doi: 10.1016/j.jcis.2024.04.086. Online ahead of print. J Colloid Interface Sci. 2024. PMID: 38640650
Furthermore, a full cell is assembled with HT-FeSe(2)/Se/C as the anode, and a vanadium-based cathode (Na(3)V(2)(PO(4))(2)O(2)F), showcasing a high specific capacity of 118.1 mAh/g at 2 A/g. The excellent performance of HT-FeSe(2)/Se/C may hint at future mate …
Furthermore, a full cell is assembled with HT-FeSe(2)/Se/C as the anode, and a vanadium-based cathode (Na(3)V(2)(PO(4))(2)O(2) …
Vascular Ehlers-Danlos Syndrome: A Comprehensive Natural History Study in a Dutch National Cohort of 142 Patients.
Demirdas S, van den Bersselaar LM, Lechner R, Bos J, Alsters SIM, Baars MJH, Baas AF, Baysal Ö, van der Crabben SN, Dulfer E, Giesbertz NAA, Helderman-van den Enden ATJM, Hilhorst-Hofstee Y, Kempers MJE, Komdeur FL, Loeys B, Majoor-Krakauer D, Ockeloen CW, Overwater E, van Tintelen PJ, Voorendt M, de Waard V, Maugeri A, Brüggenwirth HT, van de Laar IMBH, Houweling AC. Demirdas S, et al. Circ Genom Precis Med. 2024 Apr 16:e003978. doi: 10.1161/CIRCGEN.122.003978. Online ahead of print. Circ Genom Precis Med. 2024. PMID: 38623759 Free article.
Gulf toadfish (Opsanus beta) gill neuroepithelial cells in response to hypoxia exposure.
Duh OA, McDonald MD. Duh OA, et al. J Comp Physiol B. 2024 Apr 16. doi: 10.1007/s00360-024-01547-3. Online ahead of print. J Comp Physiol B. 2024. PMID: 38622281
Neuroepithelial cells (NECs) within the fish gill contain the monoamine neurochemical serotonin (5-HT), sense changes in the partial pressure of oxygen (PO(2)) in the surrounding water and blood, and initiate the cardiovascular and ventilatory responses to hypoxia. ...Juve …
Neuroepithelial cells (NECs) within the fish gill contain the monoamine neurochemical serotonin (5-HT), sense changes in the partial …
Adjustments of the Phytochemical Profile of Broccoli to Low and High Growing Temperatures: Implications for the Bioactivity of Its Extracts.
Šola I, Gmižić D, Pinterić M, Tot A, Ludwig-Müller J. Šola I, et al. Int J Mol Sci. 2024 Mar 26;25(7):3677. doi: 10.3390/ijms25073677. Int J Mol Sci. 2024. PMID: 38612494 Free PMC article.
The total glucosinolates were also increased by LT; however, they were decreased by HT. Soluble sugars, known osmoprotectants, were increased by both types of stress, considerably more by HT than LT, suggesting that HT causes a more intense osmotic imbalance. …
The total glucosinolates were also increased by LT; however, they were decreased by HT. Soluble sugars, known osmoprotectants, were i …
Prenatal co-exposure to diisodecyl phthalate and ozone contribute to depressive behavior in offspring mice through oxidative stress and TWIST1 participation.
Xie X, Yan B, Yang L, Deng L, Xue X, Gao M, Wei H, Chen S, Wu Y, Yang X, Ma P. Xie X, et al. Sci Total Environ. 2024 Apr 11;928:172411. doi: 10.1016/j.scitotenv.2024.172411. Online ahead of print. Sci Total Environ. 2024. PMID: 38608898
The study found that prenatal exposure to both DIDP and O(3) significantly increased depressive-like behavior in the offspring mice compared to either DIDP or O(3) alone. Prenatal exposure to DIDP and O(3) obviously increased the levels of corticotropin-relea …
The study found that prenatal exposure to both DIDP and O(3) significantly increased depressive-like behavior in the offspring mice c …
Determination of HLA class II risk alleles and prediction of self/non-self-epitopes contributing Hashimoto's thyroiditis in a group of Iranian patients.
Shirizadeh A, Borzouei S, Razavi Z, Taherkhani A, Faradmal J, Solgi G. Shirizadeh A, et al. Immunogenetics. 2024 Apr 12. doi: 10.1007/s00251-024-01339-7. Online ahead of print. Immunogenetics. 2024. PMID: 38607388
HLA-DRB1/-DQB1 genotyping was performed in 100 HT patients and 330 ethnically matched healthy controls to determine the predisposing/protective alleles for HT disease. ...We identified HLA-DRB1*03:01, *04:02, *04:05, and *11:04 as predisposing alleles and DRB1*13:01 …
HLA-DRB1/-DQB1 genotyping was performed in 100 HT patients and 330 ethnically matched healthy controls to determine the predisposing/ …
Metal nanoparticle-induced effects on green toads (Amphibia, Anura) under climate change: conservation implications.
Vaissi S, Chahardoli A, Haghighi ZMS, Heshmatzad P. Vaissi S, et al. Environ Sci Pollut Res Int. 2024 Apr 9. doi: 10.1007/s11356-024-33219-8. Online ahead of print. Environ Sci Pollut Res Int. 2024. PMID: 38592634
In this study, we investigated the survival, developmental, behavioral, and histological reactions of Bufotes viridis embryos and larvae exposed to different NPs for a duration of 10 days, using lethal concentrations (LC25%, LC50%, and LC75% mg/L) under both ambient (AT: 18 C) an …
In this study, we investigated the survival, developmental, behavioral, and histological reactions of Bufotes viridis embryos and larvae exp …
Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference.
Linz D, Andrade JG, Arbelo E, Boriani G, Breithardt G, Camm AJ, Caso V, Nielsen JC, De Melis M, De Potter T, Dichtl W, Diederichsen SZ, Dobrev D, Doll N, Duncker D, Dworatzek E, Eckardt L, Eisert C, Fabritz L, Farkowski M, Filgueiras-Rama D, Goette A, Guasch E, Hack G, Hatem S, Haeusler KG, Healey JS, Heidbuechel H, Hijazi Z, Hofmeister LH, Hove-Madsen L, Huebner T, Kääb S, Kotecha D, Malaczynska-Rajpold K, Merino JL, Metzner A, Mont L, Ng GA, Oeff M, Parwani AS, Puererfellner H, Ravens U, Rienstra M, Sanders P, Scherr D, Schnabel R, Schotten U, Sohns C, Steinbeck G, Steven D, Toennis T, Tzeis S, van Gelder IC, van Leerdam RH, Vernooy K, Wadhwa M, Wakili R, Willems S, Witt H, Zeemering S, Kirchhof P. Linz D, et al. Europace. 2024 Mar 30;26(4):euae070. doi: 10.1093/europace/euae070. Europace. 2024. PMID: 38591838 Free PMC article.
5,445 results