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Page 1
Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies.
Mak E, Reid RI, Przybelski SA, Lesnick TG, Schwarz CG, Senjem ML, Raghavan S, Vemuri P, Jack CR Jr, Min HK, Jain MK, Miyagawa T, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Jones DT, Botha H, St Louis EK, Knopman DS, Ramanan VK, Dickson DW, Graff-Radford NR, Ferman TJ, Petersen RC, Lowe VJ, Boeve BF, O'Brien JT, Kantarci K. Mak E, et al. NPJ Parkinsons Dis. 2024 Apr 3;10(1):76. doi: 10.1038/s41531-024-00684-4. NPJ Parkinsons Dis. 2024. PMID: 38570511 Free PMC article.
The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor and AI-based multi-professional data interpretation.
Golubnitschaja O, Polivka J Jr, Potuznik P, Pesta M, Stetkarova I, Mazurakova A, Lackova L, Kubatka P, Kropp M, Thumann G, Erb C, Fröhlich H, Wang W, Baban B, Kapalla M, Shapira N, Richter K, Karabatsiakis A, Smokovski I, Schmeel LC, Gkika E, Paul F, Parini P, Polivka J. Golubnitschaja O, et al. EPMA J. 2024 Feb 27;15(1):1-23. doi: 10.1007/s13167-024-00356-6. eCollection 2024 Mar. EPMA J. 2024. PMID: 38463624 Free PMC article.
Sex Differences in Outcomes of Late-Window Endovascular Stroke Therapy.
Abdalkader M, Ning S, Qureshi MM, Haussen DC, Strbian D, Nagel S, Demeestere J, Puetz V, Mohammaden MH, Olive Gadea M, Winzer S, Yamagami H, Tanaka K, Marto JP, Tomppo L, Henon H, Sheth SA, Ortega-Gutierrez S, Martinez-Majander N, Caparros F, Lemmens R, Dusart A, Bellante F, Zaidi SF, Siegler JE, Nannoni S, Kaesmacher J, Dobrocky T, Farooqui M, Salazar-Marioni S, Virtanen P, Vandewalle L, Wouters A, Jesser J, Ventura R, Castonguay AC, Uchida K, Puri AS, Masoud HE, Klein P, Mansoor Z, Bui J, Kang M, Mujanovic A, Rizzo F, Kokkonen T, Ramos JN, Strambo D, Michel P, Möhlenbruch MA, Lin E, Kaiser DPO, Yoshimura S, Sakai N, Cordonnier C, Ringleb PA, Roy D, Zaidat OO, Fischer U, Ribo M, Raymond J, Nogueira RG, Nguyen TN. Abdalkader M, et al. Stroke. 2024 Feb;55(2):278-287. doi: 10.1161/STROKEAHA.123.045015. Epub 2024 Jan 22. Stroke. 2024. PMID: 38252759
Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial.
Pant S, Wainberg ZA, Weekes CD, Furqan M, Kasi PM, Devoe CE, Leal AD, Chung V, Basturk O, VanWyk H, Tavares AM, Seenappa LM, Perry JR, Kheoh T, McNeil LK, Welkowsky E, DeMuth PC, Haqq CM, O'Reilly EM. Pant S, et al. Nat Med. 2024 Feb;30(2):531-542. doi: 10.1038/s41591-023-02760-3. Epub 2024 Jan 9. Nat Med. 2024. PMID: 38195752 Free PMC article. Clinical Trial.
Docking for Molecules That Bind in a Symmetric Stack with SymDOCK.
Smith MS, Knight IS, Kormos RC, Pepe JG, Kunach P, Diamond MI, Shahmoradian SH, Irwin JJ, DeGrado WF, Shoichet BK. Smith MS, et al. J Chem Inf Model. 2024 Jan 22;64(2):425-434. doi: 10.1021/acs.jcim.3c01749. Epub 2024 Jan 8. J Chem Inf Model. 2024. PMID: 38191997 Free PMC article.
More convincingly, in a prospective study, SymDOCK predicted the structure of the PET tracer MK-6240 bound in a symmetrical stack to AD PHF tau before that structure was determined; the docked pose was used to determine how MK-6240 fit the cryo-EM density. In proof-of-conc …
More convincingly, in a prospective study, SymDOCK predicted the structure of the PET tracer MK-6240 bound in a symmetrical stack to AD PHF …
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability.
Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD. Gorman J, et al. Nat Commun. 2024 Jan 4;15(1):285. doi: 10.1038/s41467-023-44534-y. Nat Commun. 2024. PMID: 38177144 Free PMC article.
To gain insight into LASV neutralization, here we develop a prefusion-stabilized LASV glycoprotein trimer (GPC), pan it against phage libraries comprising single-domain antibodies (nanobodies) from shark and camel, and identify one, D5, which neutralizes LASV. Cryo-EM anal …
To gain insight into LASV neutralization, here we develop a prefusion-stabilized LASV glycoprotein trimer (GPC), pan it against phage librar …
Docking for molecules that bind in a symmetric stack with SymDOCK.
Smith MS, Knight IS, Kormos RC, Pepe JG, Kunach P, Diamond MI, Shahmoradian SH, Irwin JJ, DeGrado WF, Shoichet BK. Smith MS, et al. bioRxiv [Preprint]. 2023 Oct 29:2023.10.27.564400. doi: 10.1101/2023.10.27.564400. bioRxiv. 2023. PMID: 37961414 Free PMC article. Updated. Preprint.
More convincingly, in a prospective study SymDOCK predicted the structure of the PET tracer MK-6240 bound in a symmetrical stack to AD PHF tau before that structure was determined; the docked pose was used to determine how MK-6240 fit the cryo-EM density. In proof-of-conce …
More convincingly, in a prospective study SymDOCK predicted the structure of the PET tracer MK-6240 bound in a symmetrical stack to AD PHF t …
Mapping density, diversity and species-richness of the Amazon tree flora.
Ter Steege H, Pitman NCA, do Amaral IL, de Souza Coelho L, de Almeida Matos FD, de Andrade Lima Filho D, Salomão RP, Wittmann F, Castilho CV, Guevara JE, Veiga Carim MJ, Phillips OL, Magnusson WE, Sabatier D, Revilla JDC, Molino JF, Irume MV, Martins MP, da Silva Guimarães JR, Ramos JF, Bánki OS, Piedade MTF, Cárdenas López D, Rodrigues DJ, Demarchi LO, Schöngart J, Almeida EJ, Barbosa LF, Cavalheiro L, Dos Santos MCV, Luize BG, de Leão Novo EMM, Vargas PN, Silva TSF, Venticinque EM, Manzatto AG, Reis NFC, Terborgh J, Casula KR, Honorio Coronado EN, Monteagudo Mendoza A, Montero JC, Costa FRC, Feldpausch TR, Quaresma AC, Castaño Arboleda N, Zartman CE, Killeen TJ, Marimon BS, Marimon-Junior BH, Vasquez R, Mostacedo B, Assis RL, Baraloto C, do Amaral DD, Engel J, Petronelli P, Castellanos H, de Medeiros MB, Simon MF, Andrade A, Camargo JL, Laurance WF, Laurance SGW, Maniguaje Rincón L, Schietti J, Sousa TR, de Sousa Farias E, Lopes MA, Magalhães JLL, Nascimento HEM, de Queiroz HL, Aymard C GA, Brienen R, Stevenson PR, Araujo-Murakami A, Baker TR, Cintra BBL, Feitosa YO, Mogollón HF, Duivenvoorden JF, Peres CA, Silman MR, Ferreira LV, Lozada JR, Comiskey JA, Draper FC, de Toledo JJ,… See abstract for full author list ➔ Ter Steege H, et al. Commun Biol. 2023 Nov 8;6(1):1130. doi: 10.1038/s42003-023-05514-6. Commun Biol. 2023. PMID: 37938615 Free PMC article.
259 results