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Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals.
Allen KN, Torres-Velarde JM, Vazquez JM, Moreno-Santillán DD, Sudmant PH, Vázquez-Medina JP. Allen KN, et al. BMC Biol. 2024 Apr 23;22(1):91. doi: 10.1186/s12915-024-01892-3. BMC Biol. 2024. PMID: 38654271
Hence, we developed a proliferative arterial endothelial cell culture model from elephant seals and used RNA-seq, functional assays, and confocal microscopy to assess the molecular response to prolonged hypoxia. RESULTS: Seal and human endothelial cells exposed to 1% O(2) …
Hence, we developed a proliferative arterial endothelial cell culture model from elephant seals and used RNA-seq, functional assays, and con …
Exome sequencing in extreme altitude mountaineers identifies pathogenic variants in RTEL1 and COL6A1 previously associated with respiratory failure.
Maksiutenko EM, Merkureva V, Barbitoff YA, Tsay VV, Aseev MV, Glotov AS, Glotov OS. Maksiutenko EM, et al. Physiol Rep. 2024 Apr;12(8):e16015. doi: 10.14814/phy2.16015. Physiol Rep. 2024. PMID: 38653581
To our surprise, we identified two putative loss-of-function variants, rs1385101139 in RTEL1 and rs1002726737 in COL6A1 in two extremely high altitude (personal record of more than 8500 m) professional climbers. Both variants can be interpreted as pathogenic according to m …
To our surprise, we identified two putative loss-of-function variants, rs1385101139 in RTEL1 and rs1002726737 in COL6A1 in two extremely hig …
Synthesis and biological properties of novel glucose-based macromolecular architectures.
Indla NR, Maruthi Y, Rawat R, Kumar TS, Reddy NR, Sharma M, Aminabhavi TM, Kakarla RR, Sesha Sainath AV. Indla NR, et al. Int J Biol Macromol. 2024 Apr 21:131724. doi: 10.1016/j.ijbiomac.2024.131724. Online ahead of print. Int J Biol Macromol. 2024. PMID: 38653427
In this research, ABA- and AB-type glucose-based biological macromolecules were synthesized using acryl-2,3,4,6-tetra-O-acetyl-D-glucopyranoside with pentafluorophenyl (FPM), pentafluorobenzyl (FBM), phenyl (PM) and benzyl (BM) methacrylate-based macro-RAFT agents followin …
In this research, ABA- and AB-type glucose-based biological macromolecules were synthesized using acryl-2,3,4,6-tetra-O-acetyl-D-gluc …
Magnetic exchange interactions and non-Debye relaxation in Spin-3/2 Frustrated Kagome Magnet Co(3)V(2)O(8).
Singh H, Skoulatos M, Joshi DC, Pramanik P, RoyChowdhury M, Ghosh S, Jena SK, Dey JK, Thota S. Singh H, et al. J Phys Condens Matter. 2024 Apr 23. doi: 10.1088/1361-648X/ad4223. Online ahead of print. J Phys Condens Matter. 2024. PMID: 38653255

The magnetic contribution of the C(P)-T near T(N)has been analyzed using the power-law expression C(M)= A|T - TN|(-alpha)resulting in the critical exponent alpha = 0.18 0.01 (0.15 0.003) for T < T(N)(T > T(N)), respectively for the Co(3)V(2)O(8). It is interes

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The magnetic contribution of the C(P)-T near T(N)has been analyzed using the power-law expression C(M)= A|T - TN|(-alpha)resulting in …
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Takahashi M, Chong HB, Zhang S, Yang TY, Lazarov MJ, Harry S, Maynard M, Hilbert B, White RD, Murrey HE, Tsou CC, Vordermark K, Assaad J, Gohar M, Dürr BR, Richter M, Patel H, Kryukov G, Brooijmans N, Alghali ASO, Rubio K, Villanueva A, Zhang J, Ge M, Makram F, Griesshaber H, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Popoola G, Rachmin I, Khandelwal N, Neil JR, Tien PC, Chen N, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Kastanos J, Oh E, Fisher DE, Maheswaran S, Haber DA, Boland GM, Sade-Feldman M, Jenkins RW, Hata AN, Bardeesy NM, Suvà ML, Martin BR, Liau BB, Ott CJ, Rivera MN, Lawrence MS, Bar-Peled L. Takahashi M, et al. Cell. 2024 Apr 17:S0092-8674(24)00318-0. doi: 10.1016/j.cell.2024.03.027. Online ahead of print. Cell. 2024. PMID: 38653237
Binder-free all-carbon composite supercapacitors.
Jarrar S, Hussain S, Haq AU, Bhattacharya G, Saadeddin I, Servera L, Ruiz JM, Janem A, Daraghmeh A. Jarrar S, et al. Nanotechnology. 2024 Apr 23. doi: 10.1088/1361-6528/ad41e9. Online ahead of print. Nanotechnology. 2024. PMID: 38653208
.% GNPs which is around 5-fold higher in value than the pristine CNFs in 1 M KOH, which then further increased to 189 F g-1 in 6 M KOH electrolyte. ...
.% GNPs which is around 5-fold higher in value than the pristine CNFs in 1 M KOH, which then further increased to 189 F g-1 in 6 M …
Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease.
Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, Kimmich O, Wiltfang J, Bartels C, Hansen N, Jessen F, Rostamzadeh A, Düzel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Wagner M, Roeske S, Heneka MT, Brosseron F, Ramirez A, Dobisch L, Wolfsgruber S, Kleineidam L, Yakupov R, Stark M, Schmid MC, Berger M, Hetzer S, Dechent P, Scheffler K, Petzold GC, Schneider A, Effland A, Radbruch A. Deike K, et al. Invest Radiol. 2024 Apr 23. doi: 10.1097/RLI.0000000000001077. Online ahead of print. Invest Radiol. 2024. PMID: 38652067
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