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Colon cancer stem cells.
Kreso A, O'Brien CA. Kreso A, et al. Curr Protoc Stem Cell Biol. 2008 Nov;Chapter 3:Unit 3.1. doi: 10.1002/9780470151808.sc0301s7. Curr Protoc Stem Cell Biol. 2008. PMID: 19016431
Cancer stem cells in solid tumors: an overview.
O'Brien CA, Kreso A, Dick JE. O'Brien CA, et al. Semin Radiat Oncol. 2009 Apr;19(2):71-7. doi: 10.1016/j.semradonc.2008.11.001. Semin Radiat Oncol. 2009. PMID: 19249644 Review.
Cancer stem cells and self-renewal.
O'Brien CA, Kreso A, Jamieson CH. O'Brien CA, et al. Clin Cancer Res. 2010 Jun 15;16(12):3113-20. doi: 10.1158/1078-0432.CCR-09-2824. Epub 2010 Jun 8. Clin Cancer Res. 2010. PMID: 20530701 Review.
Self-renewal as a therapeutic target in human colorectal cancer.
Kreso A, van Galen P, Pedley NM, Lima-Fernandes E, Frelin C, Davis T, Cao L, Baiazitov R, Du W, Sydorenko N, Moon YC, Gibson L, Wang Y, Leung C, Iscove NN, Arrowsmith CH, Szentgyorgyi E, Gallinger S, Dick JE, O'Brien CA. Kreso A, et al. Nat Med. 2014 Jan;20(1):29-36. doi: 10.1038/nm.3418. Epub 2013 Dec 1. Nat Med. 2014. PMID: 24292392
Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, Guicherit O, Wouters BG, O'Brien CA, Shields D, Olson P, VanArsdale T, Weinrich SL, Rejto P, Christensen JG, Fantin VR, Hung KE, Martin ES. Belmont PJ, et al. Sci Signal. 2014 Nov 11;7(351):ra107. doi: 10.1126/scisignal.2005516. Sci Signal. 2014. PMID: 25389372
159 results