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Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds.
Haugh MG, Murphy CM, McKiernan RC, Altenbuchner C, O'Brien FJ. Haugh MG, et al. Tissue Eng Part A. 2011 May;17(9-10):1201-8. doi: 10.1089/ten.TEA.2010.0590. Epub 2011 Jan 17. Tissue Eng Part A. 2011. PMID: 21155630
A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes.
Farrell E, O'Brien FJ, Doyle P, Fischer J, Yannas I, Harley BA, O'Connell B, Prendergast PJ, Campbell VA. Farrell E, et al. Tissue Eng. 2006 Mar;12(3):459-68. doi: 10.1089/ten.2006.12.459. Tissue Eng. 2006. PMID: 16579679
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering.
O'Brien FJ, Harley BA, Waller MA, Yannas IV, Gibson LJ, Prendergast PJ. O'Brien FJ, et al. Technol Health Care. 2007;15(1):3-17. Technol Health Care. 2007. PMID: 17264409
Design and validation of a dynamic flow perfusion bioreactor for use with compliant tissue engineering scaffolds.
Jaasma MJ, Plunkett NA, O'Brien FJ. Jaasma MJ, et al. J Biotechnol. 2008 Feb 29;133(4):490-6. doi: 10.1016/j.jbiotec.2007.11.010. Epub 2007 Dec 8. J Biotechnol. 2008. PMID: 18221813
Development of a collagen calcium-phosphate scaffold as a novel bone graft substitute.
Al-Munajjed AA, Gleeson JP, O'Brien FJ. Al-Munajjed AA, et al. Stud Health Technol Inform. 2008;133:11-20. Stud Health Technol Inform. 2008. PMID: 18376009
The effect of dehydrothermal treatment on the mechanical and structural properties of collagen-GAG scaffolds.
Haugh MG, Jaasma MJ, O'Brien FJ. Haugh MG, et al. J Biomed Mater Res A. 2009 May;89(2):363-9. doi: 10.1002/jbm.a.31955. J Biomed Mater Res A. 2009. PMID: 18431763
Mechanical stimulation of osteoblasts using steady and dynamic fluid flow.
Jaasma MJ, O'Brien FJ. Jaasma MJ, et al. Tissue Eng Part A. 2008 Jul;14(7):1213-23. doi: 10.1089/ten.tea.2007.0321. Tissue Eng Part A. 2008. PMID: 18433309
Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation.
Byrne EM, Farrell E, McMahon LA, Haugh MG, O'Brien FJ, Campbell VA, Prendergast PJ, O'Connell BC. Byrne EM, et al. J Mater Sci Mater Med. 2008 Nov;19(11):3455-63. doi: 10.1007/s10856-008-3506-2. Epub 2008 Jun 27. J Mater Sci Mater Med. 2008. PMID: 18584120
Osteoblast activity on collagen-GAG scaffolds is affected by collagen and GAG concentrations.
Tierney CM, Jaasma MJ, O'Brien FJ. Tierney CM, et al. J Biomed Mater Res A. 2009 Oct;91(1):92-101. doi: 10.1002/jbm.a.32207. J Biomed Mater Res A. 2009. PMID: 18767061
Part 1: scaffolds and surfaces.
Lyons F, Partap S, O'Brien FJ. Lyons F, et al. Technol Health Care. 2008;16(4):305-17. Technol Health Care. 2008. PMID: 18776607 No abstract available.
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