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The copy-number of plasmids and other genetic elements can be determined by SYBR-Green-based quantitative real-time PCR.
Providenti MA, O'Brien JM, Ewing RJ, Paterson ES, Smith ML. Providenti MA, et al. J Microbiol Methods. 2006 Jun;65(3):476-87. doi: 10.1016/j.mimet.2005.09.007. Epub 2005 Oct 10. J Microbiol Methods. 2006. PMID: 16216354
The locus coding for the 3-nitrobenzoate dioxygenase of Comamonas sp. strain JS46 is flanked by IS1071 elements and is subject to deletion and inversion events.
Providenti MA, Shaye RE, Lynes KD, McKenna NT, O'brien JM, Rosolen S, Wyndham RC, Lambert IB. Providenti MA, et al. Appl Environ Microbiol. 2006 Apr;72(4):2651-60. doi: 10.1128/AEM.72.4.2651-2660.2006. Appl Environ Microbiol. 2006. PMID: 16597970 Free PMC article.
Metabolism of isovanillate, vanillate, and veratrate by Comamonas testosteroni strain BR6020.
Providenti MA, O'Brien JM, Ruff J, Cook AM, Lambert IB. Providenti MA, et al. J Bacteriol. 2006 Jun;188(11):3862-9. doi: 10.1128/JB.01675-05. J Bacteriol. 2006. PMID: 16707678 Free PMC article.
Transcriptional profiles in the cerebral hemisphere of chicken embryos following in ovo perfluorohexane sulfonate exposure.
Cassone CG, Taylor JJ, O'Brien JM, Williams A, Yauk CL, Crump D, Kennedy SW. Cassone CG, et al. Toxicol Sci. 2012 Oct;129(2):380-91. doi: 10.1093/toxsci/kfs219. Epub 2012 Jul 12. Toxicol Sci. 2012. PMID: 22790973
Time-dependent transcriptomic and biochemical responses of 6-formylindolo[3,2-b]carbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are explained by AHR activation time.
Farmahin R, Crump D, O'Brien JM, Jones SP, Kennedy SW. Farmahin R, et al. Biochem Pharmacol. 2016 Sep 1;115:134-43. doi: 10.1016/j.bcp.2016.06.005. Epub 2016 Jun 11. Biochem Pharmacol. 2016. PMID: 27301797
Pipping success and liver mRNA expression in chicken embryos exposed in ovo to C8 and C11 perfluorinated carboxylic acids and C10 perfluorinated sulfonate.
O'Brien JM, Crump D, Mundy LJ, Chu S, McLaren KK, Vongphachan V, Letcher RJ, Kennedy SW. O'Brien JM, et al. Toxicol Lett. 2009 Oct 28;190(2):134-9. doi: 10.1016/j.toxlet.2009.07.004. Epub 2009 Jul 10. Toxicol Lett. 2009. PMID: 19595750
Exposure to 3,3',4,4',5-pentachlorobiphenyl during embryonic development has a minimal effect on the cytochrome P4501A response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in cultured chicken embryo hepatocytes.
Head JA, O'Brien J, Kennedy SW. Head JA, et al. Environ Toxicol Chem. 2006 Nov;25(11):2981-9. doi: 10.1897/05-520r.1. Environ Toxicol Chem. 2006. PMID: 17089722
Perfluorooctane sulfonate (PFOS) toxicity in domestic chicken (Gallus gallus domesticus) embryos in the absence of effects on peroxisome proliferator activated receptor alpha (PPARalpha)-regulated genes.
O'Brien JM, Carew AC, Chu S, Letcher RJ, Kennedy SW. O'Brien JM, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2009 May;149(4):524-30. doi: 10.1016/j.cbpc.2008.11.009. Epub 2008 Dec 6. Comp Biochem Physiol C Toxicol Pharmacol. 2009. PMID: 19101656
Technical-grade perfluorooctane sulfonate alters the expression of more transcripts in cultured chicken embryonic hepatocytes than linear perfluorooctane sulfonate.
O'Brien JM, Austin AJ, Williams A, Yauk CL, Crump D, Kennedy SW. O'Brien JM, et al. Environ Toxicol Chem. 2011 Dec;30(12):2846-59. doi: 10.1002/etc.700. Environ Toxicol Chem. 2011. PMID: 21994020
Folate deficiency increases chromosomal damage and mutations in hematopoietic cells in the transgenic mutamouse model.
LeBlanc DP, Behan NA, O'Brien JM, Marchetti F, MacFarlane AJ. LeBlanc DP, et al. Environ Mol Mutagen. 2018 Jun;59(5):366-374. doi: 10.1002/em.22190. Epub 2018 Apr 18. Environ Mol Mutagen. 2018. PMID: 29668043
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