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208 results
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Inhibition of beta-catenin translocation in rodent colorectal tumors: a novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer.
Brown WA, Skinner SA, Vogiagis D, O'Brien PE. Brown WA, et al. Dig Dis Sci. 2001 Nov;46(11):2314-21. doi: 10.1023/a:1012326525692. Dig Dis Sci. 2001. PMID: 11713928
Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model.
Malcontenti-Wilson C, Muralidharan V, Skinner S, Christophi C, Sherris D, O'Brien PE. Malcontenti-Wilson C, et al. Clin Cancer Res. 2001 Apr;7(4):1052-60. Clin Cancer Res. 2001. PMID: 11309357
5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer.
Brown WA, Farmer KC, Skinner SA, Malcontenti-Wilson C, Misajon A, O'Brien PE. Brown WA, et al. Dig Dis Sci. 2000 Aug;45(8):1578-84. doi: 10.1023/a:1005517112039. Dig Dis Sci. 2000. PMID: 11007109
Expression of adhesion molecules and leukocyte recruitment into gastric mucosa following ischemia-reperfusion.
Andrews FJ, Malcontenti-Wilson C, O'Brien PE. Andrews FJ, et al. Dig Dis Sci. 1997 Feb;42(2):326-32. doi: 10.1023/a:1018813902094. Dig Dis Sci. 1997. PMID: 9052514
Changes in sulfated macromolecules produced in vivo during normal and indomethacin-delayed ulcer healing in rats.
Lyons KC, Andrews FJ, Comper WD, O'Brien PE. Lyons KC, et al. Dig Dis Sci. 1997 Aug;42(8):1755-64. doi: 10.1023/a:1018830002964. Dig Dis Sci. 1997. PMID: 9286245
Non-steroidal anti-inflammatory drugs with different cyclooxygenase inhibitory profiles that prevent aberrant crypt foci formation but vary in acute gastrotoxicity in a rat model.
Brown WA, Skinner SA, Malcontenti-Wilson C, Misajon A, DeJong T, Vogiagis D, O'Brien PE. Brown WA, et al. J Gastroenterol Hepatol. 2000 Dec;15(12):1386-92. doi: 10.1046/j.1440-1746.2000.02370.x. J Gastroenterol Hepatol. 2000. PMID: 11197048
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation.
Brown WA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, O'Brien PE. Brown WA, et al. Gut. 2001 May;48(5):660-6. doi: 10.1136/gut.48.5.660. Gut. 2001. PMID: 11302965 Free PMC article.
Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels.
Vogiagis D, Brown W, Glare EM, O'Brien PE. Vogiagis D, et al. Carcinogenesis. 2001 Jun;22(6):869-74. doi: 10.1093/carcin/22.6.869. Carcinogenesis. 2001. PMID: 11375891
Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation.
de Jong TA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, Bailey M, van Driel IR, O'Brien PE. de Jong TA, et al. Am J Physiol Gastrointest Liver Physiol. 2000 Feb;278(2):G266-72. doi: 10.1152/ajpgi.2000.278.2.G266. Am J Physiol Gastrointest Liver Physiol. 2000. PMID: 10666051
Sulindac inhibits colorectal tumour growth, but not prostaglandin synthesis in the rat.
Charalambous D, Skinner SA, O'Brien PE. Charalambous D, et al. J Gastroenterol Hepatol. 1998 Dec;13(12):1195-200. J Gastroenterol Hepatol. 1998. PMID: 9918425
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