O'Brien PJ - Search Results

1

Modulating hypoxia-induced hepatocyte injury by affecting intracellular redox state.

Khan S, O'Brien PJ. Khan S, et al. Biochim Biophys Acta. 1995 Nov 9;1269(2):153-61. doi: 10.1016/0167-4889(95)00112-6. Biochim Biophys Acta. 1995. PMID: 7488648

2

Role of cytochrome P-450IIE1 in N-nitroso-N-methylaniline induced hepatocyte cytotoxicity.

Quan Z, Khan S, O'Brien PJ. Quan Z, et al. Chem Biol Interact. 1992 Aug 28;83(3):221-33. doi: 10.1016/0009-2797(92)90099-7. Chem Biol Interact. 1992. PMID: 1516150

3

The antidotal activity of the thiol drug diethyldithiocarbamate against N-acetyl-p-benzoquinone imine in isolated hepatocytes.

Lauriault VV, O'Brien PJ. Lauriault VV, et al. Adv Exp Med Biol. 1991;283:311-4. doi: 10.1007/978-1-4684-5877-0_38. Adv Exp Med Biol. 1991. PMID: 1648865 No abstract available.

4

Catecholic iron complexes as cytoprotective superoxide scavengers against hypoxia:reoxygenation injury in isolated hepatocytes.

Zhao ZS, Khan S, O'Brien PJ. Zhao ZS, et al. Biochem Pharmacol. 1998 Oct 1;56(7):825-30. doi: 10.1016/s0006-2952(98)00222-6. Biochem Pharmacol. 1998. PMID: 9774144

5

Oxygen dependence of hepatocyte susceptibility to mitochondrial respiratory inhibitors.

Niknahad H, Khan S, O'Brien PJ. Niknahad H, et al. Biochem Pharmacol. 1995 Nov 27;50(11):1859-65. doi: 10.1016/0006-2952(95)02079-9. Biochem Pharmacol. 1995. PMID: 8615865

6

Molecular mechanisms of SR 4233-induced hepatocyte toxicity under aerobic versus hypoxic conditions.

Silva JM, O'Brien PJ. Silva JM, et al. Br J Cancer. 1993 Sep;68(3):484-91. doi: 10.1038/bjc.1993.374. Br J Cancer. 1993. PMID: 8394729 Free PMC article.

7

S-nitrosyl glutathione-mediated hepatocyte cytotoxicity.

Meloche BA, O'Brien PJ. Meloche BA, et al. Xenobiotica. 1993 Aug;23(8):863-71. doi: 10.3109/00498259309059414. Xenobiotica. 1993. PMID: 8284942

8

Cytotoxicity induced by N-methyl-N'-nitro-N-nitrosoguanidine may involve S-nitrosyl glutathione and nitric oxide.

Niknahad H, O'Brien PJ. Niknahad H, et al. Xenobiotica. 1995 Jan;25(1):91-101. doi: 10.3109/00498259509061836. Xenobiotica. 1995. PMID: 7604611

9

Prevention of nitrofurantoin-induced cytotoxicity in isolated hepatocytes by fructose.

Silva JM, McGirr L, O'Brien PJ. Silva JM, et al. Arch Biochem Biophys. 1991 Sep;289(2):313-8. doi: 10.1016/0003-9861(91)90416-g. Arch Biochem Biophys. 1991. PMID: 1898074

10

Molecular mechanism for prevention of N-acetyl-p-benzoquinoneimine cytotoxicity by the permeable thiol drugs diethyldithiocarbamate and dithiothreitol.

Lauriault VV, O'Brien PJ. Lauriault VV, et al. Mol Pharmacol. 1991 Jul;40(1):125-34. Mol Pharmacol. 1991. PMID: 1649964

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