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82 results
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Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy.
O'Connor AE, Gallagher WM, Byrne AT. O'Connor AE, et al. Photochem Photobiol. 2009 Sep-Oct;85(5):1053-74. doi: 10.1111/j.1751-1097.2009.00585.x. Epub 2009 Aug 3. Photochem Photobiol. 2009. PMID: 19682322 Review.
Mechanism of cell death mediated by a BF2-chelated tetraaryl-azadipyrromethene photodynamic therapeutic: dissection of the apoptotic pathway in vitro and in vivo.
O'Connor AE, Mc Gee MM, Likar Y, Ponomarev V, Callanan JJ, O'shea DF, Byrne AT, Gallagher WM. O'Connor AE, et al. Int J Cancer. 2012 Feb 1;130(3):705-15. doi: 10.1002/ijc.26073. Epub 2011 May 26. Int J Cancer. 2012. PMID: 21413012 Free PMC article.
Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells.
O'Donovan N, Byrne AT, O'Connor AE, McGee S, Gallagher WM, Crown J. O'Donovan N, et al. Invest New Drugs. 2011 Oct;29(5):752-9. doi: 10.1007/s10637-010-9415-5. Epub 2010 Mar 16. Invest New Drugs. 2011. PMID: 20229355
The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate.
O'Connor S, Szwej E, Nikodinovic-Runic J, O'Connor A, Byrne AT, Devocelle M, O'Donovan N, Gallagher WM, Babu R, Kenny ST, Zinn M, Zulian QR, O'Connor KE. O'Connor S, et al. Biomaterials. 2013 Apr;34(11):2710-8. doi: 10.1016/j.biomaterials.2012.12.032. Epub 2013 Jan 21. Biomaterials. 2013. PMID: 23343631
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.
Fitzpatrick SF, Tambuwala MM, Bruning U, Schaible B, Scholz CC, Byrne A, O'Connor A, Gallagher WM, Lenihan CR, Garvey JF, Howell K, Fallon PG, Cummins EP, Taylor CT. Fitzpatrick SF, et al. J Immunol. 2011 Jan 15;186(2):1091-6. doi: 10.4049/jimmunol.1002256. Epub 2010 Dec 13. J Immunol. 2011. PMID: 21149600
Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.
Li B, Ni Chonghaile T, Fan Y, Madden SF, Klinger R, O'Connor AE, Walsh L, O'Hurley G, Mallya Udupi G, Joseph J, Tarrant F, Conroy E, Gaber A, Chin SF, Bardwell HA, Provenzano E, Crown J, Dubois T, Linn S, Jirstrom K, Caldas C, O'Connor DP, Gallagher WM. Li B, et al. Cancer Res. 2017 Jul 15;77(14):3834-3845. doi: 10.1158/0008-5472.CAN-16-2546. Epub 2017 Apr 28. Cancer Res. 2017. PMID: 28455421
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells.
Hams E, Saunders SP, Cummins EP, O'Connor A, Tambuwala MT, Gallagher WM, Byrne A, Campos-Torres A, Moynagh PM, Jobin C, Taylor CT, Fallon PG. Hams E, et al. Shock. 2011 Sep;36(3):295-302. doi: 10.1097/SHK.0b013e318225ad7e. Shock. 2011. PMID: 21844787 Free PMC article.
A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
FitzGerald J, Murillo LS, O'Brien G, O'Connell E, O'Connor A, Wu K, Wang GN, Rainey MD, Natoni A, Healy S, O'Dwyer M, Santocanale C. FitzGerald J, et al. PLoS One. 2014 Jun 5;9(6):e98891. doi: 10.1371/journal.pone.0098891. eCollection 2014. PLoS One. 2014. PMID: 24902048 Free PMC article.
Programmed Cell Death 2-like (Pdcd2l) Is Required for Mouse Embryonic Development.
Houston BJ, Oud MS, Aguirre DM, Merriner DJ, O'Connor AE, Okutman O, Viville S, Burke R, Veltman JA, O'Bryan MK. Houston BJ, et al. Among authors: o connor ae. G3 (Bethesda). 2020 Oct 14:g3.401714.2020. doi: 10.1534/g3.120.401714. Online ahead of print. G3 (Bethesda). 2020. PMID: 33055224 Free article.
A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer.
Dwane L, O'Connor AE, Das S, Moran B, Mulrane L, Pinto-Fernandez A, Ward E, Blümel AM, Cavanagh BL, Mooney B, Dirac AM, Jirström K, Kessler BM, Ní Chonghaile T, Bernards R, Gallagher WM, O'Connor DP. Dwane L, et al. Among authors: o connor ae. Cancer Res. 2020 Nov 15;80(22):5076-5088. doi: 10.1158/0008-5472.CAN-20-0214. Epub 2020 Oct 1. Cancer Res. 2020. PMID: 33004351
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