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Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.
Tcheandjieu C, Zhu X, Hilliard AT, Clarke SL, Napolioni V, Ma S, Lee KM, Fang H, Chen F, Lu Y, Tsao NL, Raghavan S, Koyama S, Gorman BR, Vujkovic M, Klarin D, Levin MG, Sinnott-Armstrong N, Wojcik GL, Plomondon ME, Maddox TM, Waldo SW, Bick AG, Pyarajan S, Huang J, Song R, Ho YL, Buyske S, Kooperberg C, Haessler J, Loos RJF, Do R, Verbanck M, Chaudhary K, North KE, Avery CL, Graff M, Haiman CA, Le Marchand L, Wilkens LR, Bis JC, Leonard H, Shen B, Lange LA, Giri A, Dikilitas O, Kullo IJ, Stanaway IB, Jarvik GP, Gordon AS, Hebbring S, Namjou B, Kaufman KM, Ito K, Ishigaki K, Kamatani Y, Verma SS, Ritchie MD, Kember RL, Baras A, Lotta LA; Regeneron Genetics Center; CARDIoGRAMplusC4D Consortium; Biobank Japan; Million Veteran Program; Kathiresan S, Hauser ER, Miller DR, Lee JS, Saleheen D, Reaven PD, Cho K, Gaziano JM, Natarajan P, Huffman JE, Voight BF, Rader DJ, Chang KM, Lynch JA, Damrauer SM, Wilson PWF, Tang H, Sun YV, Tsao PS, O'Donnell CJ, Assimes TL. Tcheandjieu C, et al. Nat Med. 2022 Aug;28(8):1679-1692. doi: 10.1038/s41591-022-01891-3. Epub 2022 Aug 1. Nat Med. 2022. PMID: 35915156 Free PMC article.
Aging syndrome genes and premature coronary artery disease.
Low AF, O'Donnell CJ, Kathiresan S, Everett B, Chae CU, Shaw SY, Ellinor PT, MacRae CA. Low AF, et al. BMC Med Genet. 2005 Oct 31;6:38. doi: 10.1186/1471-2350-6-38. BMC Med Genet. 2005. PMID: 16262891 Free PMC article.
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O'Donnell CJ, Hirschhorn JN, Kääb S, Spooner PM, Meitinger T, Chakravarti A. Arking DE, et al. Nat Genet. 2006 Jun;38(6):644-51. doi: 10.1038/ng1790. Epub 2006 Apr 30. Nat Genet. 2006. PMID: 16648850
Matrix Gla protein is associated with risk factors for atherosclerosis but not with coronary artery calcification.
O'Donnell CJ, Shea MK, Price PA, Gagnon DR, Wilson PW, Larson MG, Kiel DP, Hoffmann U, Ferencik M, Clouse ME, Williamson MK, Cupples LA, Dawson-Hughes B, Booth SL. O'Donnell CJ, et al. Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2769-74. doi: 10.1161/01.ATV.0000245793.83158.06. Epub 2006 Sep 14. Arterioscler Thromb Vasc Biol. 2006. PMID: 16973975 Free PMC article.
743 results