O'Loughlin K - Search Results

1

Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats.

Moaddel R, Sanghvi M, Ramamoorthy A, Jozwiak K, Singh N, Green C, O'Loughlin K, Torjman M, Wainer IW. Moaddel R, et al. J Pharm Biomed Anal. 2016 Aug 5;127:3-8. doi: 10.1016/j.jpba.2016.03.030. Epub 2016 Mar 14. J Pharm Biomed Anal. 2016. PMID: 27017097 Free PMC article.

2

Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate.

Coughlin JE, Pandey RK, Padmanabhan S, O'Loughlin KG, Marquis J, Green CE, Mirsalis JC, Iyer RP. Coughlin JE, et al. Drug Metab Dispos. 2012 May;40(5):970-81. doi: 10.1124/dmd.111.044446. Epub 2012 Feb 10. Drug Metab Dispos. 2012. PMID: 22328581 Free PMC article.

3

Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu.

Sammeta SM, Wang L, Mutyam SK, O'Loughlin K, Green CE, Werner MH, Kelly T, Shankar GN. Sammeta SM, et al. Pharm Dev Technol. 2015 Mar;20(2):169-75. doi: 10.3109/10837450.2013.852574. Epub 2013 Nov 13. Pharm Dev Technol. 2015. PMID: 24218989

4

(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.

Paul RK, Singh NS, Khadeer M, Moaddel R, Sanghvi M, Green CE, O'Loughlin K, Torjman MC, Bernier M, Wainer IW. Paul RK, et al. Anesthesiology. 2014 Jul;121(1):149-59. doi: 10.1097/ALN.0000000000000285. Anesthesiology. 2014. PMID: 24936922 Free PMC article.

5

Pharmacokinetics and Metabolism of 4R-Cembranoid.

Vélez-Carrasco W, Green CE, Catz P, Furimsky A, O'Loughlin K, Eterović VA, Ferchmin PA. Vélez-Carrasco W, et al. PLoS One. 2015 Mar 26;10(3):e0121540. doi: 10.1371/journal.pone.0121540. eCollection 2015. PLoS One. 2015. PMID: 25811857 Free PMC article.

6

The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats.

Moaddel R, Sanghvi M, Dossou KS, Ramamoorthy A, Green C, Bupp J, Swezey R, O'Loughlin K, Wainer IW. Moaddel R, et al. Pharmacol Res Perspect. 2015 Aug;3(4):e00157. doi: 10.1002/prp2.157. Epub 2015 Jun 22. Pharmacol Res Perspect. 2015. PMID: 26171236 Free PMC article.

7

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.

Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB. Ekins S, et al. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01711-17. doi: 10.1128/AAC.01711-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133569 Free PMC article.

8

Granulocyte Colony-Stimulating Factor (Neupogen®; Filgrastim) Accelerates Neutrophil Recovery in a Rodent Model of Sulfur Mustard-Induced Hematologic Toxicity.

Beske PH, Harvilchuck JA, Gibbs ST, Green CE, Iyer L, O'Loughlin K, Hu TC, Nealy MS, Platoff GE Jr, Yeung DT. Beske PH, et al. Among authors: o loughlin k. Disaster Med Public Health Prep. 2023 Dec 4;17:e550. doi: 10.1017/dmp.2023.13. Disaster Med Public Health Prep. 2023. PMID: 38044835

9

Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs.

Coughlin JE, Padmanabhan S, Zhang G, Kirk CJ, Govardhan CP, Korba BE, O'Loughlin K, Green CE, Mirsalis J, Morrey JD, Iyer RP. Coughlin JE, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1783-6. doi: 10.1016/j.bmcl.2010.01.010. Epub 2010 Jan 11. Bioorg Med Chem Lett. 2010. PMID: 20117930 Free PMC article.

10

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.

Cong Y, Dyall J, Hart BJ, DeWald LE, Johnson JC, Postnikova E, Zhou H, Gross R, Rojas O, Alexander I, Josleyn N, Zhang T, Michelotti J, Janosko K, Glass PJ, Flint M, McMullan LK, Spiropoulou CF, Mierzwa T, Guha R, Shinn P, Michael S, Klumpp-Thomas C, McKnight C, Thomas C, Eakin AE, O'Loughlin KG, Green CE, Catz P, Mirsalis JC, Honko AN, Olinger GG Jr, Bennett RS, Holbrook MR, Hensley LE, Jahrling PB. Cong Y, et al. PLoS One. 2016 Nov 30;11(11):e0166318. doi: 10.1371/journal.pone.0166318. eCollection 2016. PLoS One. 2016. PMID: 27902714 Free PMC article.

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