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Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Mishra A, Liu S, Promes J, Harata M, Sivitz W, Fink B, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens S, King T, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum J, Imai Y. Mishra A, et al. Among authors: o neill bt. JCI Insight. 2021 May 10;6(9):e144341. doi: 10.1172/jci.insight.144341. JCI Insight. 2021. PMID: 33784258 Free PMC article.
Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle.
Bhardwaj G, Penniman CM, Jena J, Suarez Beltran PA, Foster C, Poro K, Junck TL, Hinton AO Jr, Souvenir R, Fuqua JD, Morales PE, Bravo-Sagua R, Sivitz WI, Lira VA, Abel ED, O'Neill BT. Bhardwaj G, et al. Among authors: o neill bt. J Clin Invest. 2021 Sep 15;131(18):e146415. doi: 10.1172/JCI146415. J Clin Invest. 2021. PMID: 34343133 Free PMC article.
Functional resilience of C57BL/6J mouse heart to dietary fat overload.
Tadinada SM, Weatherford ET, Collins GV, Bhardwaj G, Cochran J, Kutschke W, Zimmerman K, Bosko A, O'Neill BT, Weiss RM, Abel ED. Tadinada SM, et al. Among authors: o neill bt. Am J Physiol Heart Circ Physiol. 2021 Nov 1;321(5):H850-H864. doi: 10.1152/ajpheart.00419.2021. Epub 2021 Sep 3. Am J Physiol Heart Circ Physiol. 2021. PMID: 34477461 Free PMC article.
Loss of FoxOs in muscle increases strength and mitochondrial function during aging.
Penniman CM, Bhardwaj G, Nowers CJ, Brown CU, Junck TL, Boyer CK, Jena J, Fuqua JD, Lira VA, O'Neill BT. Penniman CM, et al. Among authors: o neill bt. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):243-259. doi: 10.1002/jcsm.13124. Epub 2022 Nov 28. J Cachexia Sarcopenia Muscle. 2023. PMID: 36442857 Free PMC article.
66 results