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508 results
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Monogenic obesity in humans.
Farooqi IS, O'Rahilly S. Farooqi IS, et al. Annu Rev Med. 2005;56:443-58. doi: 10.1146/annurev.med.56.062904.144924. Annu Rev Med. 2005. PMID: 15660521 Review.
Molecular scanning of the insulin receptor gene in syndromes of insulin resistance.
Krook A, Kumar S, Laing I, Boulton AJ, Wass JA, O'Rahilly S. Krook A, et al. Diabetes. 1994 Mar;43(3):357-68. doi: 10.2337/diab.43.3.357. Diabetes. 1994. PMID: 8314008
Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution.
Montague CT, Prins JB, Sanders L, Digby JE, O'Rahilly S. Montague CT, et al. Diabetes. 1997 Mar;46(3):342-7. doi: 10.2337/diab.46.3.342. Diabetes. 1997. PMID: 9032087
Science, medicine, and the future. Non-insulin dependent diabetes mellitus: the gathering storm.
O'Rahilly S. O'Rahilly S. BMJ. 1997 Mar 29;314(7085):955-9. doi: 10.1136/bmj.314.7085.955. BMJ. 1997. PMID: 9099123 Free PMC article. Review.
Congenital leptin deficiency is associated with severe early-onset obesity in humans.
Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S. Montague CT, et al. Nature. 1997 Jun 26;387(6636):903-8. doi: 10.1038/43185. Nature. 1997. PMID: 9202122
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene.
Jackson RS, Creemers JW, Ohagi S, Raffin-Sanson ML, Sanders L, Montague CT, Hutton JC, O'Rahilly S. Jackson RS, et al. Nat Genet. 1997 Jul;16(3):303-6. doi: 10.1038/ng0797-303. Nat Genet. 1997. PMID: 9207799
Molecular mechanisms of inherited insulin resistance.
Baynes KC, Whitehead J, Krook A, O'Rahilly S. Baynes KC, et al. QJM. 1997 Sep;90(9):557-62. doi: 10.1093/qjmed/90.9.557. QJM. 1997. PMID: 9349447 Review. No abstract available.
ob gene mutations and human obesity.
Farooqi S, Rau H, Whitehead J, O'Rahilly S. Farooqi S, et al. Proc Nutr Soc. 1998 Aug;57(3):471-5. doi: 10.1079/pns19980067. Proc Nutr Soc. 1998. PMID: 9794006 Review. No abstract available.
Truncated human leptin (delta133) associated with extreme obesity undergoes proteasomal degradation after defective intracellular transport.
Rau H, Reaves BJ, O'Rahilly S, Whitehead JP. Rau H, et al. Endocrinology. 1999 Apr;140(4):1718-23. doi: 10.1210/endo.140.4.6670. Endocrinology. 1999. PMID: 10098508
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.
Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes IA, McCamish MA, O'Rahilly S. Farooqi IS, et al. N Engl J Med. 1999 Sep 16;341(12):879-84. doi: 10.1056/NEJM199909163411204. N Engl J Med. 1999. PMID: 10486419 No abstract available.
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