O'Shea EK - Search Results

1

Global analysis of protein localization in budding yeast.

Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Huh WK, et al. Nature. 2003 Oct 16;425(6959):686-91. doi: 10.1038/nature02026. Nature. 2003. PMID: 14562095

2

A quantitative model of transcription factor-activated gene expression.

Kim HD, O'Shea EK. Kim HD, et al. Nat Struct Mol Biol. 2008 Nov;15(11):1192-8. doi: 10.1038/nsmb.1500. Epub 2008 Oct 12. Nat Struct Mol Biol. 2008. PMID: 18849996 Free PMC article.

3

Encoding four gene expression programs in the activation dynamics of a single transcription factor.

Hansen AS, O'Shea EK. Hansen AS, et al. Curr Biol. 2016 Apr 4;26(7):R269-71. doi: 10.1016/j.cub.2016.02.058. Curr Biol. 2016. PMID: 27046808

4

cis Determinants of Promoter Threshold and Activation Timescale.

Hansen AS, O'Shea EK. Hansen AS, et al. Cell Rep. 2015 Aug 25;12(8):1226-33. doi: 10.1016/j.celrep.2015.07.035. Epub 2015 Aug 13. Cell Rep. 2015. PMID: 26279577

5

High-throughput microfluidics to control and measure signaling dynamics in single yeast cells.

Hansen AS, Hao N, O'Shea EK. Hansen AS, et al. Nat Protoc. 2015 Aug;10(8):1181-97. doi: 10.1038/nprot.2015.079. Epub 2015 Jul 9. Nat Protoc. 2015. PMID: 26158443 Free PMC article.

6

Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast.

Zid BM, O'Shea EK. Zid BM, et al. Nature. 2014 Oct 2;514(7520):117-21. doi: 10.1038/nature13578. Epub 2014 Aug 3. Nature. 2014. PMID: 25119046 Free PMC article.

7

Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression.

Hansen AS, O'Shea EK. Hansen AS, et al. Mol Syst Biol. 2013 Nov 5;9:704. doi: 10.1038/msb.2013.56. Mol Syst Biol. 2013. PMID: 24189399 Free PMC article.

8

Hog1 controls global reallocation of RNA Pol II upon osmotic shock in Saccharomyces cerevisiae.

Cook KE, O'Shea EK. Cook KE, et al. G3 (Bethesda). 2012 Sep;2(9):1129-36. doi: 10.1534/g3.112.003251. Epub 2012 Sep 1. G3 (Bethesda). 2012. PMID: 22973550 Free PMC article.

9

Signal-dependent dynamics of transcription factor translocation controls gene expression.

Hao N, O'Shea EK. Hao N, et al. Nat Struct Mol Biol. 2011 Dec 18;19(1):31-9. doi: 10.1038/nsmb.2192. Nat Struct Mol Biol. 2011. PMID: 22179789 Free PMC article.

10

Integrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4.

Zhou X, O'Shea EK. Zhou X, et al. Mol Cell. 2011 Jun 24;42(6):826-36. doi: 10.1016/j.molcel.2011.05.025. Mol Cell. 2011. PMID: 21700227 Free PMC article.

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