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Jaks and STATs: biological implications.
Leonard WJ, O'Shea JJ. Leonard WJ, et al. Annu Rev Immunol. 1998;16:293-322. doi: 10.1146/annurev.immunol.16.1.293. Annu Rev Immunol. 1998. PMID: 9597132 Review.
Expression of the human epidermal growth factor receptor in a murine T-cell hybridoma. A transmembrane protein tyrosine kinase can synergize with the T-cell antigen receptor.
Kennedy IC, June CH, O'Shea JJ. Kennedy IC, et al. J Biol Chem. 1992 Mar 5;267(7):4924-9. J Biol Chem. 1992. PMID: 1537871
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.
Russell SM, Tayebi N, Nakajima H, Riedy MC, Roberts JL, Aman MJ, Migone TS, Noguchi M, Markert ML, Buckley RH, O'Shea JJ, Leonard WJ. Russell SM, et al. Science. 1995 Nov 3;270(5237):797-800. doi: 10.1126/science.270.5237.797. Science. 1995. PMID: 7481768
Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases.
Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ. Johnston JA, et al. J Biol Chem. 1995 Dec 1;270(48):28527-30. doi: 10.1074/jbc.270.48.28527. J Biol Chem. 1995. PMID: 7499365
Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7.
Musso T, Johnston JA, Linnekin D, Varesio L, Rowe TK, O'Shea JJ, McVicar DW. Musso T, et al. J Exp Med. 1995 Apr 1;181(4):1425-31. doi: 10.1084/jem.181.4.1425. J Exp Med. 1995. PMID: 7535338 Free PMC article.
Similarities and differences in signal transduction by interleukin 4 and interleukin 13: analysis of Janus kinase activation.
Keegan AD, Johnston JA, Tortolani PJ, McReynolds LJ, Kinzer C, O'Shea JJ, Paul WE. Keegan AD, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7681-5. doi: 10.1073/pnas.92.17.7681. Proc Natl Acad Sci U S A. 1995. PMID: 7544000 Free PMC article.
Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3.
Bacon CM, Tortolani PJ, Shimosaka A, Rees RC, Longo DL, O'Shea JJ. Bacon CM, et al. FEBS Lett. 1995 Aug 14;370(1-2):63-8. doi: 10.1016/0014-5793(95)00796-c. FEBS Lett. 1995. PMID: 7544303
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.
Migone TS, Lin JX, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard WJ. Migone TS, et al. Science. 1995 Jul 7;269(5220):79-81. doi: 10.1126/science.7604283. Science. 1995. PMID: 7604283
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.
Bacon CM, Petricoin EF 3rd, Ortaldo JR, Rees RC, Larner AC, Johnston JA, O'Shea JJ. Bacon CM, et al. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7307-11. doi: 10.1073/pnas.92.16.7307. Proc Natl Acad Sci U S A. 1995. PMID: 7638186 Free PMC article.
Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.
Tortolani PJ, Johnston JA, Bacon CM, McVicar DW, Shimosaka A, Linnekin D, Longo DL, O'Shea JJ. Tortolani PJ, et al. Blood. 1995 Jun 15;85(12):3444-51. Blood. 1995. PMID: 7780132
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