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1,448 results
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COX-derived prostanoid pathways in gastrointestinal cancer development and progression: novel targets for prevention and intervention.
Cathcart MC, O'Byrne KJ, Reynolds JV, O'Sullivan J, Pidgeon GP. Cathcart MC, et al. Biochim Biophys Acta. 2012 Jan;1825(1):49-63. doi: 10.1016/j.bbcan.2011.09.004. Epub 2011 Oct 1. Biochim Biophys Acta. 2012. PMID: 22015819 Review.
Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer.
Sullivan S, Tosetto M, Kevans D, Coss A, Wang L, O'Donoghue D, Hyland J, Sheahan K, Mulcahy H, O'Sullivan J. Sullivan S, et al. Int J Cancer. 2009 Jul 1;125(1):54-61. doi: 10.1002/ijc.24275. Int J Cancer. 2009. PMID: 19291794
Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer.
Picardo SL, Maher SG, O'Sullivan JN, Reynolds JV. Picardo SL, et al. Dig Surg. 2012;29(3):251-60. doi: 10.1159/000341498. Epub 2012 Aug 3. Dig Surg. 2012. PMID: 22868386 Review.
Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?
O'Sullivan KE, Reynolds JV, O'Hanlon C, O'Sullivan JN, Lysaght J. O'Sullivan KE, et al. J Gastrointest Cancer. 2014 Mar;45(1):1-11. doi: 10.1007/s12029-013-9555-x. J Gastrointest Cancer. 2014. PMID: 24163144 Review.
The role of inflammation in cancer of the esophagus.
O'Sullivan KE, Phelan JJ, O'Hanlon C, Lysaght J, O'Sullivan JN, Reynolds JV. O'Sullivan KE, et al. Expert Rev Gastroenterol Hepatol. 2014 Sep;8(7):749-60. doi: 10.1586/17474124.2014.913478. Epub 2014 May 23. Expert Rev Gastroenterol Hepatol. 2014. PMID: 24857183 Review.
Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma.
Lynam-Lennon N, Maher SG, Maguire A, Phelan J, Muldoon C, Reynolds JV, O'Sullivan J. Lynam-Lennon N, et al. PLoS One. 2014 Jun 26;9(6):e100738. doi: 10.1371/journal.pone.0100738. eCollection 2014. PLoS One. 2014. PMID: 24968221 Free PMC article.
Impact of the inflammatory microenvironment on T-cell phenotype in the progression from reflux oesophagitis to Barrett oesophagus and oesophageal adenocarcinoma.
Kavanagh ME, Conroy MJ, Clarke NE, Gilmartin NT, O'Sullivan KE, Feighery R, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Lysaght J. Kavanagh ME, et al. Cancer Lett. 2016 Jan 1;370(1):117-24. doi: 10.1016/j.canlet.2015.10.019. Epub 2015 Oct 28. Cancer Lett. 2016. PMID: 26519754
Emerging Concepts Linking Obesity with the Hallmarks of Cancer.
Donohoe CL, Lysaght J, O'Sullivan J, Reynolds JV. Donohoe CL, et al. Trends Endocrinol Metab. 2017 Jan;28(1):46-62. doi: 10.1016/j.tem.2016.08.004. Epub 2016 Sep 12. Trends Endocrinol Metab. 2017. PMID: 27633129 Review.
Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer.
Murphy AG, Casey R, Maguire A, Tosetto M, Butler CT, Conroy E, Reynolds AL, Sheahan K, O'Donoghue D, Gallagher WM, Fennelly D, Kennedy BN, O'Sullivan J. Murphy AG, et al. Sci Rep. 2016 Oct 14;6:34523. doi: 10.1038/srep34523. Sci Rep. 2016. PMID: 27739445 Free PMC article.
HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients.
Dunne MR, Michielsen AJ, O'Sullivan KE, Cathcart MC, Feighery R, Doyle B, Watson JA, O'Farrell NJ, Ravi N, Kay E, Reynolds JV, Ryan EJ, O'Sullivan J. Dunne MR, et al. Cancer Immunol Immunother. 2017 Jul;66(7):841-850. doi: 10.1007/s00262-017-1983-1. Epub 2017 Mar 18. Cancer Immunol Immunother. 2017. PMID: 28315927 Free PMC article.
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