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The cobT gene of Salmonella typhimurium encodes the NaMN: 5,6-dimethylbenzimidazole phosphoribosyltransferase responsible for the synthesis of N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loop of cobalamin.
Trzebiatowski JR, O'Toole GA, Escalante-Semerena JC. Trzebiatowski JR, et al. J Bacteriol. 1994 Jun;176(12):3568-75. doi: 10.1128/jb.176.12.3568-3575.1994. J Bacteriol. 1994. PMID: 8206834 Free PMC article.
Identification of a new prp locus required for propionate catabolism in Salmonella typhimurium LT2.
Hammelman TA, O'Toole GA, Trzebiatowski JR, Tsang AW, Rank D, Escalante-Semerena JC. Hammelman TA, et al. FEMS Microbiol Lett. 1996 Apr 1;137(2-3):233-9. doi: 10.1111/j.1574-6968.1996.tb08111.x. FEMS Microbiol Lett. 1996. PMID: 8998991
CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2.
Brushaber KR, O'Toole GA, Escalante-Semerena JC. Brushaber KR, et al. J Biol Chem. 1998 Jan 30;273(5):2684-91. doi: 10.1074/jbc.273.5.2684. J Biol Chem. 1998. PMID: 9446573
The global carbon metabolism regulator Crc is a component of a signal transduction pathway required for biofilm development by Pseudomonas aeruginosa.
O'Toole GA, Gibbs KA, Hager PW, Phibbs PV Jr, Kolter R. O'Toole GA, et al. J Bacteriol. 2000 Jan;182(2):425-31. doi: 10.1128/jb.182.2.425-431.2000. J Bacteriol. 2000. PMID: 10629189 Free PMC article.
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