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Superparamagnetic Spinel-Ferrite Nano-Adsorbents Adapted for Hg2+, Dy3+, Tb3+ Removal/Recycling: Synthesis, Characterization, and Assessment of Toxicity.
Allwin Mabes Raj AFP, Bauman M, Dimitrušev N, Ali LMA, Onofre M, Gary-Bobo M, Durand JO, Lobnik A, Košak A. Allwin Mabes Raj AFP, et al. Among authors: kosak a. Int J Mol Sci. 2023 Jun 13;24(12):10072. doi: 10.3390/ijms241210072. Int J Mol Sci. 2023. PMID: 37373219 Free PMC article.
In the present work, superparamagnetic adsorbents based on 3-aminopropyltrimethoxy silane (APTMS)-coated maghemite (gammaFe(2)O(3)@SiO(2)-NH(2)) and cobalt ferrite (CoFe(2)O(4)@SiO(2)-NH(2)) nanoparticles were prepared and characterized using transmission-electron m …
In the present work, superparamagnetic adsorbents based on 3-aminopropyltrimethoxy silane (APTMS)-coated maghemite (gammaFe(2)O(3)@Si …
Synthesis and characterization of novel gamma-Fe(2)O(3)-NH(4)OH@SiO(2)(APTMS) nanoparticles for dysprosium adsorption.
Kegl T, Ban I, Lobnik A, Košak A. Kegl T, et al. Among authors: kosak a. J Hazard Mater. 2019 Oct 15;378:120764. doi: 10.1016/j.jhazmat.2019.120764. Epub 2019 Jun 11. J Hazard Mater. 2019. PMID: 31203116
This paper deals with synthesis and characterization of novel gamma-Fe(2)O(3)-NH(4)OH@SiO(2)(APTMS) nanoparticles formed from magnetic gamma-Fe(2)O(3) core, stabilized electrostatically in basic media NH(4)OH, doped with SiO(2) shell and functionalized with 3-aminop …
This paper deals with synthesis and characterization of novel gamma-Fe(2)O(3)-NH(4)OH@SiO(2)(APTMS) nanoparticles formed from magneti …
Targeting Glutathione S-transferase M4 in Ewing sarcoma.
Zhuo R, Kosak KM, Sankar S, Wiles ET, Sun Y, Zhang J, Ayello J, Prestwich GD, Shami PJ, Cairo MS, Lessnick SL, Luo W. Zhuo R, et al. Among authors: kosak km. Front Pediatr. 2014 Aug 6;2:83. doi: 10.3389/fped.2014.00083. eCollection 2014. Front Pediatr. 2014. PMID: 25147782 Free PMC article.
To exploit our observation that GSTM4 expression is specifically up-regulated in Ewing sarcoma, we tested the effect of a GSTM4-activated anti-cancer agent, O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate or JS-K, on tumor growth and s …
To exploit our observation that GSTM4 expression is specifically up-regulated in Ewing sarcoma, we tested the effect of a GSTM4-activated an …
Effect of a Pluronic(®) P123 formulation on the nitric oxide-generating drug JS-K.
Kaur I, Kosak KM, Terrazas M, Herron JN, Kern SE, Boucher KM, Shami PJ. Kaur I, et al. Among authors: kosak km. Pharm Res. 2015 Apr;32(4):1395-406. doi: 10.1007/s11095-014-1542-9. Epub 2014 Oct 18. Pharm Res. 2015. PMID: 25330743 Free PMC article.
PURPOSE: O(2)-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing prodrug of the arylated diazeniumdiolate class with promising anti-tumor activity. ...
PURPOSE: O(2)-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing pr …
Cellular distribution studies of the nitric oxide-generating antineoplastic prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate formulated in Pluronic P123 micelles.
Kaur I, Terrazas M, Kosak KM, Kern SE, Boucher KM, Shami PJ. Kaur I, et al. Among authors: kosak km. J Pharm Pharmacol. 2013 Sep;65(9):1329-36. doi: 10.1111/jphp.12100. Epub 2013 Jul 10. J Pharm Pharmacol. 2013. PMID: 23927471 Free PMC article.
It induces differentiation and apoptosis in acute myeloid leukaemia (AML) cells. The NO prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate, or JS-K, has potent antileukaemic activity. ...
It induces differentiation and apoptosis in acute myeloid leukaemia (AML) cells. The NO prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxy …
The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.
Maciag AE, Chakrapani H, Saavedra JE, Morris NL, Holland RJ, Kosak KM, Shami PJ, Anderson LM, Keefer LK. Maciag AE, et al. Among authors: kosak km. J Pharmacol Exp Ther. 2011 Feb;336(2):313-20. doi: 10.1124/jpet.110.174904. Epub 2010 Oct 20. J Pharmacol Exp Ther. 2011. PMID: 20962031 Free PMC article.
Diazeniumdiolate-based nitric oxide (NO)-releasing prodrugs are a growing class of promising NO-based therapeutics. Here, we show that O(2)-(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K) is a potent cytotoxic agent against a subset …
Diazeniumdiolate-based nitric oxide (NO)-releasing prodrugs are a growing class of promising NO-based therapeutics. Here, we show that O …
Terbium Ion Adsorption from Aqueous Solution by Using Magnetic gammaFe(2)O(3)-NH(4)OH@SiO(2) Nanoparticles Functionalized with Amino Groups.
Kegl T, Košak A, Lobnik A, Ban I. Kegl T, et al. Among authors: kosak a. Materials (Basel). 2019 Apr 19;12(8):1294. doi: 10.3390/ma12081294. Materials (Basel). 2019. PMID: 31010217 Free PMC article.
The obtained results confirm the potential of the synthesized magnetic gamma-Fe(2)O(3)-NH(4)OH@SiO(2) NPs, functionalized with (3-Aminopropyl) trimethoxysilane (APTMS), to be used for adsorption of Tb(3+) from aqueous solution, with the possibility of its removal from aque …
The obtained results confirm the potential of the synthesized magnetic gamma-Fe(2)O(3)-NH(4)OH@SiO(2) NPs, functionalized with (3-Ami …
JS-K, an arylating nitric oxide (NO) donor, has synergistic anti-leukemic activity with cytarabine (ARA-C).
Shami PJ, Maciag AE, Eddington JK, Udupi V, Kosak KM, Saavedra JE, Keefer LK. Shami PJ, et al. Among authors: kosak km. Leuk Res. 2009 Nov;33(11):1525-9. doi: 10.1016/j.leukres.2009.01.002. Epub 2009 Feb 3. Leuk Res. 2009. PMID: 19193435 Free PMC article.
This design exploits the upregulation of GST in acute myeloid leukemia (AML) cells. O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K, a member of this class) has potent anti-leukemic activity. ...
This design exploits the upregulation of GST in acute myeloid leukemia (AML) cells. O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)pip …
11 results