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Lipid remodelling in hepatocyte proliferation and hepatocellular carcinoma.
Hall Z, Chiarugi D, Charidemou E, Leslie J, Scott E, Pellegrinet L, Allison M, Mocciaro G, Anstee QM, Evan GI, Hoare M, Vidal-Puig A, Oakley F, Vacca M, Griffin JL. Hall Z, et al. Among authors: oakley f. Hepatology. 2020 May 27. doi: 10.1002/hep.31391. Online ahead of print. Hepatology. 2020. PMID: 32460431
Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy.
Oakley F, Gee LM, Sheerin NS, Borthwick LA. Oakley F, et al. Curr Opin Pharmacol. 2019 Dec;49:95-101. doi: 10.1016/j.coph.2019.10.004. Epub 2019 Nov 12. Curr Opin Pharmacol. 2019. PMID: 31731225 Free PMC article. Review.
Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1.
Oakley F, Mann J, Ruddell RG, Pickford J, Weinmaster G, Mann DA. Oakley F, et al. J Biol Chem. 2003 Jul 4;278(27):24359-70. doi: 10.1074/jbc.M211051200. Epub 2003 Apr 16. J Biol Chem. 2003. PMID: 12700242
Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis.
Oakley F, Trim N, Constandinou CM, Ye W, Gray AM, Frantz G, Hillan K, Kendall T, Benyon RC, Mann DA, Iredale JP. Oakley F, et al. Am J Pathol. 2003 Nov;163(5):1849-58. doi: 10.1016/S0002-9440(10)63544-4. Am J Pathol. 2003. PMID: 14578185 Free PMC article.
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.
Oakley F, Meso M, Iredale JP, Green K, Marek CJ, Zhou X, May MJ, Millward-Sadler H, Wright MC, Mann DA. Oakley F, et al. Gastroenterology. 2005 Jan;128(1):108-20. doi: 10.1053/j.gastro.2004.10.003. Gastroenterology. 2005. PMID: 15633128
Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury.
Oakley F, Mann J, Nailard S, Smart DE, Mungalsingh N, Constandinou C, Ali S, Wilson SJ, Millward-Sadler H, Iredale JP, Mann DA. Oakley F, et al. Am J Pathol. 2005 Mar;166(3):695-708. doi: 10.1016/s0002-9440(10)62291-2. Am J Pathol. 2005. PMID: 15743782 Free PMC article.
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis.
Mann J, Oakley F, Akiboye F, Elsharkawy A, Thorne AW, Mann DA. Mann J, et al. Cell Death Differ. 2007 Feb;14(2):275-85. doi: 10.1038/sj.cdd.4401979. Epub 2006 Jun 9. Cell Death Differ. 2007. PMID: 16763620
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