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Page 1
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression.
Azzu V, Vacca M, Kamzolas I, Hall Z, Leslie J, Carobbio S, Virtue S, Davies SE, Lukasik A, Dale M, Bohlooly-Y M, Acharjee A, Lindén D, Bidault G, Petsalaki E, Griffin JL, Oakley F, Allison MED, Vidal-Puig A. Azzu V, et al. Among authors: oakley f. Mol Metab. 2021 Jun;48:101210. doi: 10.1016/j.molmet.2021.101210. Epub 2021 Mar 17. Mol Metab. 2021. PMID: 33722690 Free PMC article.
A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.
Paish HL, Reed LH, Brown H, Bryan MC, Govaere O, Leslie J, Barksby BS, Garcia Macia M, Watson A, Xu X, Zaki MYW, Greaves L, Whitehall J, French J, White SA, Manas DM, Robinson SM, Spoletini G, Griffiths C, Mann DA, Borthwick LA, Drinnan MJ, Mann J, Oakley F. Paish HL, et al. Among authors: oakley f. Hepatology. 2019 Oct;70(4):1377-1391. doi: 10.1002/hep.30651. Epub 2019 May 28. Hepatology. 2019. PMID: 30963615 Free PMC article.
Loss of ELK1 has differential effects on age-dependent organ fibrosis.
Cairns JT, Habgood A, Edwards-Pritchard RC, Joseph C, John AE, Wilkinson C, Stewart ID, Leslie J, Blaxall BC, Susztak K, Alberti S, Nordheim A, Oakley F, Jenkins G, Tatler AL. Cairns JT, et al. Among authors: oakley f. Int J Biochem Cell Biol. 2020 Mar;120:105668. doi: 10.1016/j.biocel.2019.105668. Epub 2019 Dec 23. Int J Biochem Cell Biol. 2020. PMID: 31877385 Free PMC article.
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.
Leslie J, Millar BJ, Del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson AJ, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. Leslie J, et al. Among authors: oakley f. JCI Insight. 2020 Feb 27;5(4):e125937. doi: 10.1172/jci.insight.125937. JCI Insight. 2020. PMID: 32102985 Free PMC article.
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma.
Hall Z, Chiarugi D, Charidemou E, Leslie J, Scott E, Pellegrinet L, Allison M, Mocciaro G, Anstee QM, Evan GI, Hoare M, Vidal-Puig A, Oakley F, Vacca M, Griffin JL. Hall Z, et al. Among authors: oakley f. Hepatology. 2021 Mar;73(3):1028-1044. doi: 10.1002/hep.31391. Epub 2020 Nov 3. Hepatology. 2021. PMID: 32460431
Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis.
Vacca M, Leslie J, Virtue S, Lam BYH, Govaere O, Tiniakos D, Snow S, Davies S, Petkevicius K, Tong Z, Peirce V, Nielsen MJ, Ament Z, Li W, Kostrzewski T, Leeming DJ, Ratziu V, Allison MED, Anstee QM, Griffin JL, Oakley F, Vidal-Puig A. Vacca M, et al. Among authors: oakley f. Nat Metab. 2020 Jun;2(6):514-531. doi: 10.1038/s42255-020-0214-9. Epub 2020 Jun 8. Nat Metab. 2020. PMID: 32694734 Free PMC article.
154 results