Ober RJ - Search Results

1

Targeting FcRn to Generate Antibody-Based Therapeutics.

Ward ES, Ober RJ. Ward ES, et al. Among authors: ober rj. Trends Pharmacol Sci. 2018 Oct;39(10):892-904. doi: 10.1016/j.tips.2018.07.007. Epub 2018 Aug 22. Trends Pharmacol Sci. 2018. PMID: 30143244 Free PMC article. Review.

2

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans.

Firan M, Bawdon R, Radu C, Ober RJ, Eaken D, Antohe F, Ghetie V, Ward ES. Firan M, et al. Among authors: ober rj. Int Immunol. 2001 Aug;13(8):993-1002. doi: 10.1093/intimm/13.8.993. Int Immunol. 2001. PMID: 11470769

3

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies.

Ober RJ, Radu CG, Ghetie V, Ward ES. Ober RJ, et al. Int Immunol. 2001 Dec;13(12):1551-9. doi: 10.1093/intimm/13.12.1551. Int Immunol. 2001. PMID: 11717196

4

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans.

Ward ES, Zhou J, Ghetie V, Ober RJ. Ward ES, et al. Among authors: ober rj. Int Immunol. 2003 Feb;15(2):187-95. doi: 10.1093/intimm/dxg018. Int Immunol. 2003. PMID: 12578848

5

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

Zhou J, Johnson JE, Ghetie V, Ober RJ, Ward ES. Zhou J, et al. Among authors: ober rj. J Mol Biol. 2003 Sep 26;332(4):901-13. doi: 10.1016/s0022-2836(03)00952-5. J Mol Biol. 2003. PMID: 12972260

6

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

Ober RJ, Martinez C, Vaccaro C, Zhou J, Ward ES. Ober RJ, et al. J Immunol. 2004 Feb 15;172(4):2021-9. doi: 10.4049/jimmunol.172.4.2021. J Immunol. 2004. PMID: 14764666

7

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level.

Ober RJ, Martinez C, Lai X, Zhou J, Ward ES. Ober RJ, et al. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11076-81. doi: 10.1073/pnas.0402970101. Epub 2004 Jul 16. Proc Natl Acad Sci U S A. 2004. PMID: 15258288 Free PMC article.

8

Simultaneous imaging of different focal planes in fluorescence microscopy for the study of cellular dynamics in three dimensions.

Prabhat P, Ram S, Ward ES, Ober RJ. Prabhat P, et al. Among authors: ober rj. IEEE Trans Nanobioscience. 2004 Dec;3(4):237-42. doi: 10.1109/tnb.2004.837899. IEEE Trans Nanobioscience. 2004. PMID: 15631134 Free PMC article.

9

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis.

Zhou J, Mateos F, Ober RJ, Ward ES. Zhou J, et al. Among authors: ober rj. J Mol Biol. 2005 Feb 4;345(5):1071-81. doi: 10.1016/j.jmb.2004.11.014. Epub 2004 Dec 16. J Mol Biol. 2005. PMID: 15644205

10

From sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.

Ward ES, Martinez C, Vaccaro C, Zhou J, Tang Q, Ober RJ. Ward ES, et al. Among authors: ober rj. Mol Biol Cell. 2005 Apr;16(4):2028-38. doi: 10.1091/mbc.e04-08-0735. Epub 2005 Feb 2. Mol Biol Cell. 2005. PMID: 15689494 Free PMC article.

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