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Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.
Savage TM, Shonts BA, Obradovic A, Dewolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho SH, Tang Q, Turka LA, Shen Y, Sykes M. Savage TM, et al. JCI Insight. 2018 Nov 15;3(22):e124086. doi: 10.1172/jci.insight.124086. JCI Insight. 2018. PMID: 30429370 Free PMC article.
Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
Fu J, Zuber J, Martinez M, Shonts B, Obradovic A, Wang H, Lau SP, Xia A, Waffarn EE, Frangaj K, Savage TM, Simpson MT, Yang S, Guo XV, Miron M, Senda T, Rogers K, Rahman A, Ho SH, Shen Y, Griesemer A, Farber DL, Kato T, Sykes M. Fu J, et al. Cell Stem Cell. 2019 Feb 7;24(2):227-239.e8. doi: 10.1016/j.stem.2018.11.007. Epub 2018 Nov 29. Cell Stem Cell. 2019. PMID: 30503142 Free PMC article.
Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome.
Zuber J, Shonts B, Lau SP, Obradovic A, Fu J, Yang S, Lambert M, Coley S, Weiner J, Thome J, DeWolf S, Farber DL, Shen Y, Caillat-Zucman S, Bhagat G, Griesemer A, Martinez M, Kato T, Sykes M. Zuber J, et al. Sci Immunol. 2016 Oct;1(4):eaah3732. doi: 10.1126/sciimmunol.aah3732. Epub 2016 Oct 7. Sci Immunol. 2016. PMID: 28239678 Free PMC article.
Quantifying size and diversity of the human T cell alloresponse.
DeWolf S, Grinshpun B, Savage T, Lau SP, Obradovic A, Shonts B, Yang S, Morris H, Zuber J, Winchester R, Sykes M, Shen Y. DeWolf S, et al. JCI Insight. 2018 Aug 9;3(15):e121256. doi: 10.1172/jci.insight.121256. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089728 Free PMC article.
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance.
Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M. Sprangers B, et al. Am J Transplant. 2017 Aug;17(8):2020-2032. doi: 10.1111/ajt.14251. Epub 2017 Apr 10. Am J Transplant. 2017. PMID: 28251801 Free PMC article.
Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro.
Podestà MA, Binder C, Sellberg F, DeWolf S, Shonts B, Ho SH, Obradovic A, Waffarn E, Danzl N, Berglund D, Sykes M. Podestà MA, et al. Among authors: Obradovic A. Am J Transplant. 2020 Jan;20(1):88-100. doi: 10.1111/ajt.15533. Epub 2019 Aug 13. Am J Transplant. 2020. PMID: 31319439
Early Exposure to Ketamine Impairs Axonal Pruning in Developing Mouse Hippocampus.
Obradovic AL, Atluri N, Dalla Massara L, Oklopcic A, Todorovic NS, Katta G, Osuru HP, Jevtovic-Todorovic V. Obradovic AL, et al. Mol Neurobiol. 2018 Jan;55(1):164-172. doi: 10.1007/s12035-017-0730-0. Mol Neurobiol. 2018. PMID: 28840469 Free PMC article.
Sex-specific transcriptional signatures in human depression.
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ. Labonté B, et al. Nat Med. 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825715 Free PMC article.
CaV3.2 T-type calcium channels in peripheral sensory neurons are important for mibefradil-induced reversal of hyperalgesia and allodynia in rats with painful diabetic neuropathy.
Obradovic ALj, Hwang SM, Scarpa J, Hong SJ, Todorovic SM, Jevtovic-Todorovic V. Obradovic ALj, et al. PLoS One. 2014 Apr 4;9(4):e91467. doi: 10.1371/journal.pone.0091467. eCollection 2014. PLoS One. 2014. PMID: 24705276 Free PMC article.
Corrigendum: Sex-specific transcriptional signatures in human depression.
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kasarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ. Labonté B, et al. Nat Med. 2018 Apr 10;24(4):525. doi: 10.1038/nm0418-525d. Nat Med. 2018. PMID: 29634684
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