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Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.
Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: ochi m. Diabetes. 2003 Feb;52(2):562-7. doi: 10.2337/diabetes.52.2.562. Diabetes. 2003. PMID: 12540636
Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.
Osawa H, Niiya T, Onuma H, Murakami A, Ochi M, Nishimiya T, Ogura T, Kato K, Shimizu I, Fujii Y, Ohashi J, Yamada K, Liang SJ, Manganiello VC, Fujita-Yamaguchi Y, Makino H. Osawa H, et al. Among authors: ochi m. Mol Genet Metab. 2003 May;79(1):43-51. doi: 10.1016/s1096-7192(03)00035-0. Mol Genet Metab. 2003. PMID: 12765845
The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes.
Ochi M, Osawa H, Onuma H, Murakami A, Nishimiya T, Shimada F, Kato K, Shimizu I, Shishino K, Murase M, Fujii Y, Ohashi J, Makino H. Ochi M, et al. Diabetes Res Clin Pract. 2003 Sep;61(3):191-8. doi: 10.1016/s0168-8227(03)00119-0. Diabetes Res Clin Pract. 2003. PMID: 12965109
The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: ochi m. Am J Hum Genet. 2004 Oct;75(4):678-86. doi: 10.1086/424761. Epub 2004 Aug 26. Am J Hum Genet. 2004. PMID: 15338456 Free PMC article.
Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.
Osawa H, Onuma H, Ochi M, Murakami A, Yamauchi J, Takasuka T, Tanabe F, Shimizu I, Kato K, Nishida W, Yamada K, Tabara Y, Yasukawa M, Fujii Y, Ohashi J, Miki T, Makino H. Osawa H, et al. Among authors: ochi m. Biochem Biophys Res Commun. 2005 Sep 23;335(2):596-602. doi: 10.1016/j.bbrc.2005.07.122. Biochem Biophys Res Commun. 2005. PMID: 16087164
Serum resistin is associated with the severity of microangiopathies in type 2 diabetes.
Osawa H, Ochi M, Kato K, Yamauchi J, Nishida W, Takata Y, Kawamura R, Onuma H, Takasuka T, Shimizu I, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: ochi m. Biochem Biophys Res Commun. 2007 Apr 6;355(2):342-6. doi: 10.1016/j.bbrc.2007.01.144. Epub 2007 Feb 5. Biochem Biophys Res Commun. 2007. PMID: 17303077
Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.
Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Kohara K, Miki T, Makino H. Osawa H, et al. Among authors: ochi m. Diabetes Care. 2007 Jun;30(6):1501-6. doi: 10.2337/dc06-1936. Epub 2007 Mar 23. Diabetes Care. 2007. PMID: 17384338
1,185 results