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High prevalence of atypical adenomatous hyperplasia of the lung in autopsy specimens from elderly patients with malignant neoplasms.
Yokose T, Ito Y, Ochiai A. Yokose T, et al. Lung Cancer. 2000 Aug;29(2):125-30. doi: 10.1016/s0169-5002(00)00101-x. Lung Cancer. 2000. PMID: 10963842
Atypical adenomatous hyperplasia (AAH) is a possible precursor lesion of adenocarcinoma of the lung, but there have been no reports of AAH focusing on autopsy studies of the lungs of elderly patients, who have higher lung cancer mortality rates. ...A total of 19 AAH …
Atypical adenomatous hyperplasia (AAH) is a possible precursor lesion of adenocarcinoma of the lung, but there have been no reports o …
A monoclonal antibody capable of detecting new differentiation antigen of the stomach.
Yokozaki H, Kyo E, Ochiai A, Ito M, Ito H, Tabuchi J, Tahara E. Yokozaki H, et al. Int J Cancer. 1992 Feb 20;50(4):523-7. doi: 10.1002/ijc.2910500404. Int J Cancer. 1992. PMID: 1537616
A monoclonal antibody (MAb) was raised against a gastric adenocarcinoma cell line TMK-1 that shows parietal cell differentiation. ...In Western-blot analysis, the antigenic molecule had a molecular weight exceeding 300 kDa in the tumor tissues, but only a
A monoclonal antibody (MAb) was raised against a gastric adenocarcinoma cell line TMK-1 that shows parietal cell differentiati
Expression of epidermal growth factor receptor in human gastric and colonic carcinomas.
Yasui W, Sumiyoshi H, Hata J, Kameda T, Ochiai A, Ito H, Tahara E. Yasui W, et al. Cancer Res. 1988 Jan 1;48(1):137-41. Cancer Res. 1988. PMID: 2446740
The expression of epidermal growth factor (EGF) receptor was examined immunohistochemically in a total of 122 gastric and 61 colonic carcinomas, out of which 16 gastric and 8 colonic carcinomas were also examined by 125I-labeled EGF binding analysis and Western blotting. . …
The expression of epidermal growth factor (EGF) receptor was examined immunohistochemically in a total of 122 gastric and 61 colonic …
Establishment and characterization of cell line SFCC from clear cell adenocarcinoma of the uterine cervix.
Ochiai A, Takanashi A, Takekura N, Nakatani H, Oda N, Kameda T, Tahara E. Ochiai A, et al. Cancer. 1989 Aug 15;64(4):854-9. doi: 10.1002/1097-0142(19890815)64:4<854::aid-cncr2820640416>3.0.co;2-#. Cancer. 1989. PMID: 2472868
A human cervical clear cell adenocarcinoma cell line was established and named SFCC. The tumor cells were obtained from ascites of a 39-year-old woman who underwent a radical hysterectomy. ...SFCC cells were continuously propagated in vitro during the past 29
A human cervical clear cell adenocarcinoma cell line was established and named SFCC. The tumor cells were obtained from ascites of
Interaction between epidermal growth factor and its receptor in progression of human gastric carcinoma.
Yasui W, Hata J, Yokozaki H, Nakatani H, Ochiai A, Ito H, Tahara E. Yasui W, et al. Int J Cancer. 1988 Feb 15;41(2):211-7. doi: 10.1002/ijc.2910410209. Int J Cancer. 1988. PMID: 2828244
The expressions of epidermal growth factor (EGF) and its receptor were studied immunohistochemically in a total of 156 gastric carcinomas; 26 early and 130 advanced. ...Patients with synchronous expression of EGF and its receptor had a far poorer prognosis than thos …
The expressions of epidermal growth factor (EGF) and its receptor were studied immunohistochemically in a total of 156 gastric carcin …
Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon.
Yamashita N, Minamoto T, Ochiai A, Onda M, Esumi H. Yamashita N, et al. Gastroenterology. 1995 Feb;108(2):434-40. doi: 10.1016/0016-5085(95)90071-3. Gastroenterology. 1995. PMID: 7835585
K-ras mutation is critical in the formation of ACF, but p53 alteration could play a causal role in tumor progression....
K-ras mutation is critical in the formation of ACF, but p53 alteration could play a causal role in tumor progression....
Mutant K-ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis.
Minamoto T, Yamashita N, Ochiai A, Mai M, Sugimura T, Ronai Z, Esumi H. Minamoto T, et al. Cancer. 1995 Mar 15;75(6 Suppl):1520-6. doi: 10.1002/1097-0142(19950315)75:6+<1520::aid-cncr2820751523>3.0.co;2-l. Cancer. 1995. PMID: 7889485
As a possible genetic biomarker, K-ras mutations, which are frequently found in colorectal cancers, were analyzed in apparently normal colorectal mucosa. ...CONCLUSION: Mutant K-ras detected in apparently normal mucosa should be a useful biomarker for identifying pe …
As a possible genetic biomarker, K-ras mutations, which are frequently found in colorectal cancers, were analyzed in apparently norma …
Frequent and characteristic K-ras activation in aberrant crypt foci of colon. Is there preference among K-ras mutants for malignant progression?
Yamashita N, Minamoto T, Ochiai A, Onda M, Esumi H. Yamashita N, et al. Cancer. 1995 Mar 15;75(6 Suppl):1527-33. doi: 10.1002/1097-0142(19950315)75:6+<1527::aid-cncr2820751524>3.0.co;2-y. Cancer. 1995. PMID: 7889486
The G-T substitution in K-ras codon 12 may undergo malignant growth easily compared with G-A substitution in colorectal carcinogenesis....
The G-T substitution in K-ras codon 12 may undergo malignant growth easily compared with G-A substitution in colorectal carcinogenesi …
A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines.
Oyama T, Kanai Y, Ochiai A, Akimoto S, Oda T, Yanagihara K, Nagafuchi A, Tsukita S, Shibamoto S, Ito F, et al. Oyama T, et al. Cancer Res. 1994 Dec 1;54(23):6282-7. Cancer Res. 1994. PMID: 7954478
They form a molecular complex with catenins, a group of cytoplasmic proteins including alpha- and beta-catenins. While alpha-catenin has been demonstrated to be crucial for cadherin function, the role of beta-catenin is not yet fully understood. In this study, we an …
They form a molecular complex with catenins, a group of cytoplasmic proteins including alpha- and beta-catenins. While alpha-c …
"Very well differentiated tubular adenocarcinoma" of the stomach: its endoscopic and histopathological characteristics.
Fujii T, Yoshida S, Abe K, Saito D, Yamaguchi H, Oguro Y, Maruyama K, Ochiai A, Hirota T. Fujii T, et al. Jpn J Clin Oncol. 1994 Jun;24(3):128-34. Jpn J Clin Oncol. 1994. PMID: 8007422

Most (75%) of the 30 tub 0 EGCs were type IIc (depressed) macroscopically, despite their histological similarity to gastric adenoma which showed a high (90%) elevated appearance incidence. The incidence of small lesions, < 2 cm in diameter, was highest in gastric adenom

Most (75%) of the 30 tub 0 EGCs were type IIc (depressed) macroscopically, despite their histological similarity to gastric adenoma which sh …
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