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Page 1
Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.
Greer DM, Shemie SD, Lewis A, Torrance S, Varelas P, Goldenberg FD, Bernat JL, Souter M, Topcuoglu MA, Alexandrov AW, Baldisseri M, Bleck T, Citerio G, Dawson R, Hoppe A, Jacobe S, Manara A, Nakagawa TA, Pope TM, Silvester W, Thomson D, Al Rahma H, Badenes R, Baker AJ, Cerny V, Chang C, Chang TR, Gnedovskaya E, Han MK, Honeybul S, Jimenez E, Kuroda Y, Liu G, Mallick UK, Marquevich V, Mejia-Mantilla J, Piradov M, Quayyum S, Shrestha GS, Su YY, Timmons SD, Teitelbaum J, Videtta W, Zirpe K, Sung G. Greer DM, et al. JAMA. 2020 Sep 15;324(11):1078-1097. doi: 10.1001/jama.2020.11586. JAMA. 2020. PMID: 32761206
This is seen when (1) there is no evidence of arousal or awareness to maximal external stimulation, including noxious visual, auditory, and tactile stimulation; (2) pupils are fixed in a midsize or dilated position and are nonreactive to light; (3) corneal, oculocephalic, and …
This is seen when (1) there is no evidence of arousal or awareness to maximal external stimulation, including noxious visual, auditory, and …
Forced downward ocular deviation. Occurrence during oculovestibular testing in sedative drug-induced coma.
Simon RP. Simon RP. Arch Neurol. 1978 Jul;35(7):456-8. doi: 10.1001/archneur.1978.00500310058012. Arch Neurol. 1978. PMID: 666597
A total of 32 consecutively encountered patients, comatose from sedative-hypnotic drug overdose, were studied by caloric (oculovestibular) testing with ice water. A variety of induced lateral eye movements was observed. ...The phenomenon of forced downward ocular de …
A total of 32 consecutively encountered patients, comatose from sedative-hypnotic drug overdose, were studied by caloric (oculovestibular
Can one predict outcome of medical coma?
Plum F, Caronna JJ. Plum F, et al. Ciba Found Symp. 1975;(34):121-39. doi: 10.1002/9780470720165.ch8. Ciba Found Symp. 1975. PMID: 1045989
The combined evaluation of the motor response to stimulation and the oculovestibular (OV) reflex gives useful indicants to the outcome of medical coma. We examined 48 patients during the first 12 h and at 24 h after the onset of medical coma. ...A minimal motor score and a …
The combined evaluation of the motor response to stimulation and the oculovestibular (OV) reflex gives useful indicants to the outcom …
Alprazolam and lorazepam overdose and the absence of brainstem reflexes.
Thumtecho S, Wainipitapong S, Chunamchai S, Suteparuk S. Thumtecho S, et al. BMJ Case Rep. 2022 May 10;15(5):e248796. doi: 10.1136/bcr-2022-248796. BMJ Case Rep. 2022. PMID: 35537772 Free PMC article.
Her Glasgow Coma Scale score was E1V1M4, with pinpoint pupils and absent corneal, oculocephalic and oculovestibular reflexes. Other physical exams, laboratory testing and brain imaging were unremarkable. ...
Her Glasgow Coma Scale score was E1V1M4, with pinpoint pupils and absent corneal, oculocephalic and oculovestibular reflexes. Other p …
Management of acute neurologic syndromes in infants and children.
Shaywitz BA. Shaywitz BA. Yale J Biol Med. 1984 Jan-Feb;57(1):83-95. Yale J Biol Med. 1984. PMID: 6375166 Free PMC article. Review.
This differentiation can be effected by an easily performed assessment (Glasgow Scale) supplemented by a limited number of tests of brain stem function (pupillary responses, oculocephalic, and oculovestibular responses). ...
This differentiation can be effected by an easily performed assessment (Glasgow Scale) supplemented by a limited number of tests of b …
Prognostic factors in severe head injury.
Davis RA, Cunningham PS. Davis RA, et al. Surg Gynecol Obstet. 1984 Dec;159(6):597-604. Surg Gynecol Obstet. 1984. PMID: 6390762 Review.
Because injury to the brain stem is generally irreversible, absence of oculocephalic reflexes, oculovestibular reflexes and pupillary response and the presence of decerebrate rigidity indicate an unfavorable outcome. ...
Because injury to the brain stem is generally irreversible, absence of oculocephalic reflexes, oculovestibular reflexes and pupillary …
Determination of death by neurologic criteria around the world.
Lewis A, Bakkar A, Kreiger-Benson E, Kumpfbeck A, Liebman J, Shemie SD, Sung G, Torrance S, Greer D. Lewis A, et al. Neurology. 2020 Jul 21;95(3):e299-e309. doi: 10.1212/WNL.0000000000009888. Epub 2020 Jun 23. Neurology. 2020. PMID: 32576632
Apnea testing was mentioned in 71 (91%) protocols; there was variability in the technique and target across protocols. Ancillary testing was included as a requirement for all determinations of BD/DNC in 22 (28%) protocols. ...
Apnea testing was mentioned in 71 (91%) protocols; there was variability in the technique and target across protocols. Ancillary t
Anoxic-ischemic encephalopathy: clinical and electrophysiological associations with outcome.
Young GB, Doig G, Ragazzoni A. Young GB, et al. Neurocrit Care. 2005;2(2):159-64. doi: 10.1385/NCC:2:2:159. Neurocrit Care. 2005. PMID: 16159058
RESULTS: The following proportions recovered awareness: 2 of 18 patients with absent pupillary reflexes; 18 of 57 with preserved pupillary reflexes (p = 0.08); 2 of 32 with absent corneal reflexes; 16 of 43 with preserved corneal reflexes (p = 0.001); 0 of 15 with absent oculo
RESULTS: The following proportions recovered awareness: 2 of 18 patients with absent pupillary reflexes; 18 of 57 with preserved pupillary r …
27 results