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Transgenic short-QT syndrome 1 rabbits mimic the human disease phenotype with QT/action potential duration shortening in the atria and ventricles and increased ventricular tachycardia/ventricular fibrillation inducibility.
Odening KE, Bodi I, Franke G, Rieke R, Ryan de Medeiros A, Perez-Feliz S, Fürniss H, Mettke L, Michaelides K, Lang CN, Steinfurt J, Pantulu ND, Ziupa D, Menza M, Zehender M, Bugger H, Peyronnet R, Behrends JC, Doleschall Z, Zur Hausen A, Bode C, Jolivet G, Brunner M. Odening KE, et al. Eur Heart J. 2019 Mar 7;40(10):842-853. doi: 10.1093/eurheartj/ehy761. Eur Heart J. 2019. PMID: 30496390
Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome.
Brunner M, Peng X, Liu GX, Ren XQ, Ziv O, Choi BR, Mathur R, Hajjiri M, Odening KE, Steinberg E, Folco EJ, Pringa E, Centracchio J, Macharzina RR, Donahay T, Schofield L, Rana N, Kirk M, Mitchell GF, Poppas A, Zehender M, Koren G. Brunner M, et al. Among authors: odening ke. J Clin Invest. 2008 Jun;118(6):2246-59. doi: 10.1172/JCI33578. J Clin Invest. 2008. PMID: 18464931 Free PMC article.
Electrophysiological studies of transgenic long QT type 1 and type 2 rabbits reveal genotype-specific differences in ventricular refractoriness and His conduction.
Odening KE, Kirk M, Brunner M, Ziv O, Lorvidhaya P, Liu GX, Schofield L, Chaves L, Peng X, Zehender M, Choi BR, Koren G. Odening KE, et al. Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H643-55. doi: 10.1152/ajpheart.00074.2010. Epub 2010 Jun 25. Am J Physiol Heart Circ Physiol. 2010. PMID: 20581090 Free PMC article.
Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits.
Bentzen BH, Bahrke S, Wu K, Larsen AP, Odening KE, Franke G, Storm vańs Gravesande K, Biermann J, Peng X, Koren G, Zehender M, Bode C, Grunnet M, Brunner M. Bentzen BH, et al. Among authors: odening ke. J Cardiovasc Pharmacol. 2011 Feb;57(2):223-30. doi: 10.1097/FJC.0b013e318203a44d. J Cardiovasc Pharmacol. 2011. PMID: 21135701
102 results