Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

26 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases.
Borroto A, Reyes-Garau D, Jiménez MA, Carrasco E, Moreno B, Martínez-Pasamar S, Cortés JR, Perona A, Abia D, Blanco S, Fuentes M, Arellano I, Lobo J, Heidarieh H, Rueda J, Esteve P, Cibrián D, Martinez-Riaño A, Mendoza P, Prieto C, Calleja E, Oeste CL, Orfao A, Fresno M, Sánchez-Madrid F, Alcamí A, Bovolenta P, Martín P, Villoslada P, Morreale A, Messeguer A, Alarcon B. Borroto A, et al. Among authors: oeste cl. Sci Transl Med. 2016 Dec 21;8(370):370ra184. doi: 10.1126/scitranslmed.aaf2140. Sci Transl Med. 2016. PMID: 28003549
R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.
Mendoza P, Martínez-Martín N, Bovolenta ER, Reyes-Garau D, Hernansanz-Agustín P, Delgado P, Diaz-Muñoz MD, Oeste CL, Fernández-Pisonero I, Castellano E, Martínez-Ruiz A, Alonso-Lopez D, Santos E, Bustelo XR, Kurosaki T, Alarcón B. Mendoza P, et al. Among authors: oeste cl. Sci Signal. 2018 May 29;11(532):eaal1506. doi: 10.1126/scisignal.aal1506. Sci Signal. 2018. PMID: 29844052
A window of opportunity for cooperativity in the T Cell Receptor.
Martin-Blanco N, Blanco R, Alda-Catalinas C, Bovolenta ER, Oeste CL, Palmer E, Schamel WW, Lythe G, Molina-París C, Castro M, Alarcon B. Martin-Blanco N, et al. Among authors: oeste cl. Nat Commun. 2018 Jul 5;9(1):2618. doi: 10.1038/s41467-018-05050-6. Nat Commun. 2018. PMID: 29976994 Free PMC article.
Antigen phagocytosis by B cells is required for a potent humoral response.
Martínez-Riaño A, Bovolenta ER, Mendoza P, Oeste CL, Martín-Bermejo MJ, Bovolenta P, Turner M, Martínez-Martín N, Alarcón B. Martínez-Riaño A, et al. Among authors: oeste cl. EMBO Rep. 2018 Sep;19(9):e46016. doi: 10.15252/embr.201846016. Epub 2018 Jul 9. EMBO Rep. 2018. PMID: 29987136 Free PMC article.
RRAS2 shapes the TCR repertoire by setting the threshold for negative selection.
Martínez-Riaño A, Bovolenta ER, Boccasavia VL, Ponomarenko J, Abia D, Oeste CL, Fresno M, van Santen HM, Alarcon B. Martínez-Riaño A, et al. Among authors: oeste cl. J Exp Med. 2019 Oct 7;216(10):2427-2447. doi: 10.1084/jem.20181959. Epub 2019 Jul 19. J Exp Med. 2019. PMID: 31324740 Free PMC article.
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia.
Hortal AM, Oeste CL, Cifuentes C, Alcoceba M, Fernández-Pisonero I, Clavaín L, Tercero R, Mendoza P, Domínguez V, García-Flores M, Pintado B, Abia D, García-Macías C, Navarro-Bailón A, Bustelo XR, González M, Alarcón B. Hortal AM, et al. Among authors: oeste cl. Mol Cancer. 2022 Feb 4;21(1):35. doi: 10.1186/s12943-022-01496-x. Mol Cancer. 2022. PMID: 35120522 Free PMC article.
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.
Fernández-Pisonero I, Clavaín L, Robles-Valero J, Lorenzo-Martín LF, Caloto R, Nieto B, García-Macías C, Oeste CL, Sánchez-Martín M, Abad A, Hortal A, Caballero D, González M, Dosil M, Alarcón B, Bustelo XR. Fernández-Pisonero I, et al. Among authors: oeste cl. Cell Rep. 2022 Mar 15;38(11):110522. doi: 10.1016/j.celrep.2022.110522. Cell Rep. 2022. PMID: 35294890 Free article.
26 results