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Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons.
Oettinghaus B, Schulz JM, Restelli LM, Licci M, Savoia C, Schmidt A, Schmitt K, Grimm A, Morè L, Hench J, Tolnay M, Eckert A, D'Adamo P, Franken P, Ishihara N, Mihara K, Bischofberger J, Scorrano L, Frank S. Oettinghaus B, et al. Cell Death Differ. 2016 Jan;23(1):18-28. doi: 10.1038/cdd.2015.39. Epub 2015 Apr 24. Cell Death Differ. 2016. PMID: 25909888 Free PMC article.
Apaf1 plays a pro-survival role by regulating centrosome morphology and function.
Ferraro E, Pesaresi MG, De Zio D, Cencioni MT, Gortat A, Cozzolino M, Berghella L, Salvatore AM, Oettinghaus B, Scorrano L, Pérez-Payà E, Cecconi F. Ferraro E, et al. Among authors: oettinghaus b. J Cell Sci. 2011 Oct 15;124(Pt 20):3450-63. doi: 10.1242/jcs.086298. Epub 2011 Oct 7. J Cell Sci. 2011. PMID: 21984814 Free article.
Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.
Akbergenov R, Duscha S, Fritz AK, Juskeviciene R, Oishi N, Schmitt K, Shcherbakov D, Teo Y, Boukari H, Freihofer P, Isnard-Petit P, Oettinghaus B, Frank S, Thiam K, Rehrauer H, Westhof E, Schacht J, Eckert A, Wolfer D, Böttger EC. Akbergenov R, et al. Among authors: oettinghaus b. EMBO Rep. 2018 Nov;19(11):e46193. doi: 10.15252/embr.201846193. Epub 2018 Sep 20. EMBO Rep. 2018. PMID: 30237157 Free PMC article.
Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics.
Schmitt K, Grimm A, Dallmann R, Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K, Ripperger JA, Albrecht U, Frank S, Brown SA, Eckert A. Schmitt K, et al. Among authors: oettinghaus b. Cell Metab. 2018 Mar 6;27(3):657-666.e5. doi: 10.1016/j.cmet.2018.01.011. Epub 2018 Feb 22. Cell Metab. 2018. PMID: 29478834 Free article.