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CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.
Burington B, Yue P, Shi X, Advani R, Lau JT, Tan J, Stinson S, Stinson J, Januario T, de Vos S, Ansell S, Forero-Torres A, Fedorowicz G, Yang TT, Elkins K, Du C, Mohan S, Yu N, Modrusan Z, Seshagiri S, Yu SF, Pandita A, Koeppen H, French D, Polson AG, Offringa R, Whiting N, Ebens A, Dornan D. Burington B, et al. Among authors: offringa r. Sci Transl Med. 2011 Mar 16;3(74):74ra22. doi: 10.1126/scitranslmed.3001620. Sci Transl Med. 2011. PMID: 21411738
An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells.
Wilson NS, Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, Ross S, Vernes JM, Lu Y, Adams C, Offringa R, Kelley B, Hymowitz S, Daniel D, Meng G, Ashkenazi A. Wilson NS, et al. Among authors: offringa r. Cancer Cell. 2011 Jan 18;19(1):101-13. doi: 10.1016/j.ccr.2010.11.012. Cancer Cell. 2011. PMID: 21251615 Free article.
T cell avidity determines the level of CTL activation.
Hofmann M, Radsak M, Rechtsteiner G, Wiemann K, Günder M, Bien-Gräter U, Offringa R, Toes RE, Rammensee HG, Schild H. Hofmann M, et al. Among authors: offringa r. Eur J Immunol. 2004 Jul;34(7):1798-806. doi: 10.1002/eji.200425088. Eur J Immunol. 2004. PMID: 15214028 Free article.
250 results