Enhancing the production of physiologically active vitamin D3 by engineering the hydroxylase CYP105A1 and the electron transport chain.
Fu B, Ren Q, Ma J, Chen Q, Zhang Q, Yu P.
Fu B, et al.
World J Microbiol Biotechnol. 2021 Dec 8;38(1):14. doi: 10.1007/s11274-021-03193-1.
World J Microbiol Biotechnol. 2021.
PMID: 34877634
In this study, the conversion of vitamin D(3) (VD(3)) to its two active forms 25(OH)VD(3) and 1alpha, 25(OH)(2)VD(3) was carried out by engineering the hydroxylase CYP105A1 and its redox partners Fdx and Fdr. ...The results indicated that 2.491 mg/L of 25(OH) …
In this study, the conversion of vitamin D(3) (VD(3)) to its two active forms 25(OH)VD(3) and 1alpha, 25(OH)(2)VD(3) was carri …