Ohashi Y - Search Results

1

Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis.

Ohashi Y, Takahashi N, Terabe K, Tsuchiya S, Kojima T, Knudson CB, Knudson W, Imagama S. Ohashi Y, et al. Sci Rep. 2021 Jul 23;11(1):15131. doi: 10.1038/s41598-021-94611-9. Sci Rep. 2021. PMID: 34302034 Free PMC article.

2

Hyaluronan synthase 2 (HAS2) overexpression diminishes the procatabolic activity of chondrocytes by a mechanism independent of extracellular hyaluronan.

Ishizuka S, Tsuchiya S, Ohashi Y, Terabe K, Askew EB, Ishizuka N, Knudson CB, Knudson W. Ishizuka S, et al. Among authors: ohashi y. J Biol Chem. 2019 Sep 13;294(37):13562-13579. doi: 10.1074/jbc.RA119.008567. Epub 2019 Jul 3. J Biol Chem. 2019. PMID: 31270213 Free PMC article.

3

Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism.

Terabe K, Ohashi Y, Tsuchiya S, Ishizuka S, Knudson CB, Knudson W. Terabe K, et al. Among authors: ohashi y. J Biol Chem. 2019 Nov 22;294(47):17799-17817. doi: 10.1074/jbc.RA119.009556. Epub 2019 Oct 16. J Biol Chem. 2019. PMID: 31619518 Free PMC article.

4

Inhibition of CD44 intracellular domain production suppresses bovine articular chondrocyte de-differentiation induced by excessive mechanical stress loading.

Sobue Y, Takahashi N, Ohashi Y, Suzuki M, Nishiume T, Kobayakawa T, Terabe K, Knudson W, Knudson C, Ishiguro N, Kojima T. Sobue Y, et al. Among authors: ohashi y. Sci Rep. 2019 Oct 17;9(1):14901. doi: 10.1038/s41598-019-50166-4. Sci Rep. 2019. PMID: 31624271 Free PMC article.

5

Suppression of murine osteoarthritis by 4-methylumbelliferone.

Tsuchiya S, Ohashi Y, Ishizuka S, Ishiguro N, O'Rourke DP, Knudson CB, Knudson W. Tsuchiya S, et al. Among authors: ohashi y. J Orthop Res. 2020 May;38(5):1122-1131. doi: 10.1002/jor.24541. Epub 2019 Dec 8. J Orthop Res. 2020. PMID: 31774188 Free PMC article.

6

Hyaluronan suppresses enhanced cathepsin K expression via activation of NF-κB with mechanical stress loading in a human chondrocytic HCS-2/8 cells.

Suzuki M, Takahashi N, Sobue Y, Ohashi Y, Kishimoto K, Hattori K, Ishiguro N, Kojima T. Suzuki M, et al. Among authors: ohashi y. Sci Rep. 2020 Jan 14;10(1):216. doi: 10.1038/s41598-019-57073-8. Sci Rep. 2020. PMID: 31937805 Free PMC article.

7

Relationship between disease activity of rheumatoid arthritis and development of locomotive syndrome: A five-year longitudinal cohort study.

Sobue Y, Kojima T, Funahashi K, Okui N, Takahashi N, Asai S, Terabe K, Nishiume T, Suzuki M, Yokota Y, Ohashi Y, Ishiguro N. Sobue Y, et al. Among authors: ohashi y. Mod Rheumatol. 2021 Jan;31(1):101-107. doi: 10.1080/14397595.2020.1744828. Epub 2020 Mar 30. Mod Rheumatol. 2021. PMID: 32186235

8

Metabolic changes in synovial cells in early inflammation: Involvement of CREB phosphorylation in the anti-inflammatory effect of 2-deoxyglucose.

Kishimoto K, Terabe K, Takahashi N, Yokota Y, Ohashi Y, Hattori K, Kihira D, Maeda M, Kojima T, Imagama S. Kishimoto K, et al. Among authors: ohashi y. Arch Biochem Biophys. 2021 Sep 15;708:108962. doi: 10.1016/j.abb.2021.108962. Epub 2021 Jun 8. Arch Biochem Biophys. 2021. PMID: 34116007

9

Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway.

Hattori K, Takahashi N, Terabe K, Ohashi Y, Kishimoto K, Yokota Y, Suzuki M, Kojima T, Imagama S. Hattori K, et al. Among authors: ohashi y. Sci Rep. 2021 Jul 30;11(1):15508. doi: 10.1038/s41598-021-94938-3. Sci Rep. 2021. PMID: 34330980 Free PMC article.

10

Relationship between locomotive syndrome and frailty in rheumatoid arthritis patients by locomotive syndrome stage.

Sobue Y, Suzuki M, Ohashi Y, Koshima H, Okui N, Funahashi K, Ishikawa H, Asai S, Terabe K, Yokota Y, Kishimoto K, Takahashi N, Imagama S, Kojima T. Sobue Y, et al. Among authors: ohashi y. Mod Rheumatol. 2022 Apr 18;32(3):546-553. doi: 10.1093/mr/roab024. Mod Rheumatol. 2022. PMID: 34897498

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