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IAN family critically regulates survival and development of T lymphocytes.
Nitta T, Nasreen M, Seike T, Goji A, Ohigashi I, Miyazaki T, Ohta T, Kanno M, Takahama Y. Nitta T, et al. Among authors: ohigashi i. PLoS Biol. 2006 Apr;4(4):e103. doi: 10.1371/journal.pbio.0040103. Epub 2006 Mar 7. PLoS Biol. 2006. PMID: 16509771 Free PMC article.
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.
Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yoshikai Y, Inoue J, Akiyama T, Takahama Y. Hikosaka Y, et al. Among authors: ohigashi i. Immunity. 2008 Sep 19;29(3):438-50. doi: 10.1016/j.immuni.2008.06.018. Immunity. 2008. PMID: 18799150 Free article.
Cytokine crosstalk for thymic medulla formation.
Nitta T, Ohigashi I, Nakagawa Y, Takahama Y. Nitta T, et al. Among authors: ohigashi i. Curr Opin Immunol. 2011 Apr;23(2):190-7. doi: 10.1016/j.coi.2010.12.002. Epub 2010 Dec 30. Curr Opin Immunol. 2011. PMID: 21194915 Review.
Effects of RANKL on the thymic medulla.
Ohigashi I, Nitta T, Lkhagvasuren E, Yasuda H, Takahama Y. Ohigashi I, et al. Eur J Immunol. 2011 Jul;41(7):1822-7. doi: 10.1002/eji.201141480. Eur J Immunol. 2011. PMID: 21706487 Free article.
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