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Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.
Renner DN, Jin F, Litterman AJ, Balgeman AJ, Hanson LM, Gamez JD, Chae M, Carlson BL, Sarkaria JN, Parney IF, Ohlfest JR, Pirko I, Pavelko KD, Johnson AJ. Renner DN, et al. Among authors: ohlfest jr. PLoS One. 2015 May 1;10(5):e0125565. doi: 10.1371/journal.pone.0125565. eCollection 2015. PLoS One. 2015. PMID: 25933216 Free PMC article.
Parthenolide prodrug LC-1 slows growth of intracranial glioma.
Hexum JK, Becker CM, Kempema AM, Ohlfest JR, Largaespada DA, Harki DA. Hexum JK, et al. Among authors: ohlfest jr. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2493-5. doi: 10.1016/j.bmcl.2015.04.058. Epub 2015 Apr 25. Bioorg Med Chem Lett. 2015. PMID: 25978958
Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level.
Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ. Klank RL, et al. Among authors: ohlfest jr. Cell Rep. 2017 Jan 3;18(1):23-31. doi: 10.1016/j.celrep.2016.12.024. Cell Rep. 2017. PMID: 28052252 Free PMC article.
Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma.
Becker CM, Oberoi RK, McFarren SJ, Muldoon DM, Pafundi DH, Pokorny JL, Brinkmann DH, Ohlfest JR, Sarkaria JN, Largaespada DA, Elmquist WF. Becker CM, et al. Among authors: ohlfest jr. Neuro Oncol. 2015 Sep;17(9):1210-9. doi: 10.1093/neuonc/nov081. Epub 2015 May 12. Neuro Oncol. 2015. PMID: 25972455 Free PMC article.
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
Agarwal S, Mittapalli RK, Zellmer DM, Gallardo JL, Donelson R, Seiler C, Decker SA, Santacruz KS, Pokorny JL, Sarkaria JN, Elmquist WF, Ohlfest JR. Agarwal S, et al. Among authors: ohlfest jr. Mol Cancer Ther. 2012 Oct;11(10):2183-92. doi: 10.1158/1535-7163.MCT-12-0552. Epub 2012 Aug 13. Mol Cancer Ther. 2012. PMID: 22891038 Free PMC article.
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