Ohlmeyer M - Search Results

1

Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3.

Vincek AS, Patel J, Jaganathan A, Green A, Pierre-Louis V, Arora V, Rehmann J, Mezei M, Zhou MM, Ohlmeyer M, Mujtaba S. Vincek AS, et al. Among authors: ohlmeyer m. Molecules. 2018 Aug 2;23(8):1930. doi: 10.3390/molecules23081930. Molecules. 2018. PMID: 30072621 Free PMC article.

2

Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.

Zhang G, Plotnikov AN, Rusinova E, Shen T, Morohashi K, Joshua J, Zeng L, Mujtaba S, Ohlmeyer M, Zhou MM. Zhang G, et al. Among authors: ohlmeyer m. J Med Chem. 2013 Nov 27;56(22):9251-64. doi: 10.1021/jm401334s. Epub 2013 Nov 11. J Med Chem. 2013. PMID: 24144283 Free PMC article.

3

Integration of small-molecule discovery in academic biomedical research.

Ohlmeyer M, Zhou MM. Ohlmeyer M, et al. Mt Sinai J Med. 2010 Jul-Aug;77(4):350-7. doi: 10.1002/msj.20197. Mt Sinai J Med. 2010. PMID: 20687180 Free PMC article. Review.

4

BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.

Cheung K, Lu G, Sharma R, Vincek A, Zhang R, Plotnikov AN, Zhang F, Zhang Q, Ju Y, Hu Y, Zhao L, Han X, Meslamani J, Xu F, Jaganathan A, Shen T, Zhu H, Rusinova E, Zeng L, Zhou J, Yang J, Peng L, Ohlmeyer M, Walsh MJ, Zhang DY, Xiong H, Zhou MM. Cheung K, et al. Among authors: ohlmeyer m. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2952-2957. doi: 10.1073/pnas.1615601114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265070 Free PMC article.

5

New small molecule agonists to the thyrotropin receptor.

Latif R, Ali MR, Ma R, David M, Morshed SA, Ohlmeyer M, Felsenfeld DP, Lau Z, Mezei M, Davies TF. Latif R, et al. Among authors: ohlmeyer m. Thyroid. 2015 Jan;25(1):51-62. doi: 10.1089/thy.2014.0119. Thyroid. 2015. PMID: 25333622 Free PMC article.

6

Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.

Jin YJ, Cai CY, Mezei M, Ohlmeyer M, Sanchez R, Burakoff SJ. Jin YJ, et al. Among authors: ohlmeyer m. AIDS Res Hum Retroviruses. 2013 Apr;29(4):725-31. doi: 10.1089/AID.2012.0286. Epub 2012 Dec 31. AIDS Res Hum Retroviruses. 2013. PMID: 23151229 Free PMC article.

7

γ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizers.

Fu S, Yang Y, Das TK, Yen Y, Zhou BS, Zhou MM, Ohlmeyer M, Ko EC, Cagan R, Rosenstein BS, Chen SH, Kao J. Fu S, et al. Among authors: ohlmeyer m. PLoS One. 2012;7(6):e38465. doi: 10.1371/journal.pone.0038465. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768044 Free PMC article.

8

Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.

Zhang G, Liu R, Zhong Y, Plotnikov AN, Zhang W, Zeng L, Rusinova E, Gerona-Nevarro G, Moshkina N, Joshua J, Chuang PY, Ohlmeyer M, He JC, Zhou MM. Zhang G, et al. Among authors: ohlmeyer m. J Biol Chem. 2012 Aug 17;287(34):28840-51. doi: 10.1074/jbc.M112.359505. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645123 Free PMC article.

9

Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis.

Li CW, Menconi F, Osman R, Mezei M, Jacobson EM, Concepcion E, David CS, Kastrinsky DB, Ohlmeyer M, Tomer Y. Li CW, et al. Among authors: ohlmeyer m. J Biol Chem. 2016 Feb 19;291(8):4079-90. doi: 10.1074/jbc.M115.694687. Epub 2015 Dec 24. J Biol Chem. 2016. PMID: 26703475 Free PMC article.

10

BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy.

Segura MF, Fontanals-Cirera B, Gaziel-Sovran A, Guijarro MV, Hanniford D, Zhang G, González-Gomez P, Morante M, Jubierre L, Zhang W, Darvishian F, Ohlmeyer M, Osman I, Zhou MM, Hernando E. Segura MF, et al. Among authors: ohlmeyer m. Cancer Res. 2013 Oct 15;73(20):6264-76. doi: 10.1158/0008-5472.CAN-13-0122-T. Epub 2013 Aug 15. Cancer Res. 2013. PMID: 23950209 Free PMC article.

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