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High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice.
Huhtaniemi R, Sipilä P, Junnila A, Oksala R, Knuuttila M, Mehmood A, Aho E, Laajala TD, Aittokallio T, Laiho A, Elo L, Ohlsson C, Thulin MH, Kallio P, Mäkelä S, Mustonen MVJ, Poutanen M. Huhtaniemi R, et al. Among authors: ohlsson c. iScience. 2022 Apr 25;25(5):104287. doi: 10.1016/j.isci.2022.104287. eCollection 2022 May 20. iScience. 2022. PMID: 35573198 Free PMC article.
Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens.
Strauss L, Rantakari P, Sjögren K, Salminen A, Lauren E, Kallio J, Damdimopoulou P, Boström M, Boström PJ, Pakarinen P, Zhang F, Kujala P, Ohlsson C, Mäkelä S, Poutanen M. Strauss L, et al. Among authors: ohlsson c. FASEB J. 2013 Apr;27(4):1342-50. doi: 10.1096/fj.12-219048. Epub 2012 Dec 13. FASEB J. 2013. PMID: 23239821
Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry.
Nilsson ME, Vandenput L, Tivesten Å, Norlén AK, Lagerquist MK, Windahl SH, Börjesson AE, Farman HH, Poutanen M, Benrick A, Maliqueo M, Stener-Victorin E, Ryberg H, Ohlsson C. Nilsson ME, et al. Among authors: ohlsson c. Endocrinology. 2015 Jul;156(7):2492-502. doi: 10.1210/en.2014-1890. Epub 2015 Apr 9. Endocrinology. 2015. PMID: 25856427
Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse.
Vehmas AP, Adam M, Laajala TD, Kastenmüller G, Prehn C, Rozman J, Ohlsson C, Fuchs H, Hrabě de Angelis M, Gailus-Durner V, Elo LL, Aittokallio T, Adamski J, Corthals G, Poutanen M, Strauss L. Vehmas AP, et al. Among authors: ohlsson c. J Proteomics. 2016 Feb 5;133:66-75. doi: 10.1016/j.jprot.2015.12.009. Epub 2015 Dec 9. J Proteomics. 2016. PMID: 26691839
The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility.
Kemiläinen H, Adam M, Mäki-Jouppila J, Damdimopoulou P, Damdimopoulos AE, Kere J, Hovatta O, Laajala TD, Aittokallio T, Adamski J, Ryberg H, Ohlsson C, Strauss L, Poutanen M. Kemiläinen H, et al. Among authors: ohlsson c. Endocrinology. 2016 Oct;157(10):3719-3730. doi: 10.1210/en.2016-1252. Epub 2016 Aug 4. Endocrinology. 2016. PMID: 27490311
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Ohlsson C, Hammarstedt A, Vandenput L, Saarinen N, Ryberg H, Windahl SH, Farman HH, Jansson JO, Movérare-Skrtic S, Smith U, Zhang FP, Poutanen M, Hedjazifar S, Sjögren K. Ohlsson C, et al. Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E450-E462. doi: 10.1152/ajpendo.00093.2017. Epub 2017 Jun 27. Am J Physiol Endocrinol Metab. 2017. PMID: 28655716 Free PMC article.
746 results