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An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.
Mol Cell. 2018 Aug 16;71(4):637-648.e5. doi: 10.1016/j.molcel.2018.07.010.
Mol Cell. 2018.
PMID: 30118682
Free PMC article.
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS.
Ohol YM, et al.
Cell Host Microbe. 2010 Mar 18;7(3):210-20. doi: 10.1016/j.chom.2010.02.006.
Cell Host Microbe. 2010.
PMID: 20227664
Free PMC article.
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Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection.
Koo IC, Ohol YM, Wu P, Morisaki JH, Cox JS, Brown EJ.
Koo IC, et al. Among authors: ohol ym.
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):710-5. doi: 10.1073/pnas.0708110105. Epub 2008 Jan 7.
Proc Natl Acad Sci U S A. 2008.
PMID: 18180457
Free PMC article.
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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo.
Ohol YM, Sun MT, Cutler G, Leger PR, Hu DX, Biannic B, Rana P, Cho C, Jacobson S, Wong ST, Sanchez J, Shah N, Pookot D, Abraham B, Young K, Suthram S, Marshall LA, Bradford D, Kozon N, Han X, Okano A, Maung J, Colas C, Schwarz J, Wustrow D, Brockstedt DG, Kassner PD.
Ohol YM, et al.
Mol Cancer Ther. 2020 Oct;19(10):1970-1980. doi: 10.1158/1535-7163.MCT-20-0184. Epub 2020 Aug 11.
Mol Cancer Ther. 2020.
PMID: 32788207
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Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
Leger PR, Hu DX, Biannic B, Bui M, Han X, Karbarz E, Maung J, Okano A, Osipov M, Shibuya GM, Young K, Higgs C, Abraham B, Bradford D, Cho C, Colas C, Jacobson S, Ohol YM, Pookot D, Rana P, Sanchez J, Shah N, Sun M, Wong S, Brockstedt DG, Kassner PD, Schwarz JB, Wustrow DJ.
Leger PR, et al. Among authors: ohol ym.
J Med Chem. 2020 May 28;63(10):5398-5420. doi: 10.1021/acs.jmedchem.0c00245. Epub 2020 May 6.
J Med Chem. 2020.
PMID: 32302140
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MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Grunblatt E, Wu N, Zhang H, Liu X, Norton JP, Ohol Y, Leger P, Hiatt JB, Eastwood EC, Thomas R, Ibrahim AH, Jia D, Basom R, Eaton KD, Martins R, Houghton AM, MacPherson D.
Grunblatt E, et al.
Genes Dev. 2020 Sep 1;34(17-18):1210-1226. doi: 10.1101/gad.340133.120. Epub 2020 Aug 20.
Genes Dev. 2020.
PMID: 32820040
Free PMC article.
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Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses.
Ohol YM, Wang Z, Kemble G, Duke G.
Ohol YM, et al.
PLoS One. 2015 Dec 11;10(12):e0144648. doi: 10.1371/journal.pone.0144648. eCollection 2015.
PLoS One. 2015.
PMID: 26659560
Free PMC article.
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Patellin1, a novel Sec14-like protein, localizes to the cell plate and binds phosphoinositides.
Peterman TK, Ohol YM, McReynolds LJ, Luna EJ.
Peterman TK, et al. Among authors: ohol ym.
Plant Physiol. 2004 Oct;136(2):3080-94; discussion 3001-2. doi: 10.1104/pp.104.045369. Epub 2004 Oct 1.
Plant Physiol. 2004.
PMID: 15466235
Free PMC article.
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