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Novel investigational biologics for the treatment of cancer cachexia.
Ma JD, Heavey SF, Revta C, Roeland EJ. Ma JD, et al. Expert Opin Biol Ther. 2014 Aug;14(8):1113-20. doi: 10.1517/14712598.2014.907788. Epub 2014 Apr 7. Expert Opin Biol Ther. 2014. PMID: 24707881 Review.
AREAS COVERED: Novel therapies include ALD518, MABp1, IP-1510, OHR/AVR118, bimagrumab and REGN1033 and are discussed. For each investigational therapy, the mechanism of action, preclinical data, cachexia definition, indication and clinical data are discussed. ...
AREAS COVERED: Novel therapies include ALD518, MABp1, IP-1510, OHR/AVR118, bimagrumab and REGN1033 and are discussed. For each invest …
Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial.
Shimura M, Kitano S, Ogata N, Mitamura Y, Oh H, Ochi H, Ohsawa S, Hirakata A; YOSEMITE and RHINE Investigators. Shimura M, et al. Jpn J Ophthalmol. 2023 May;67(3):264-279. doi: 10.1007/s10384-023-00979-8. Epub 2023 Mar 10. Jpn J Ophthalmol. 2023. PMID: 36897413 Free PMC article. Clinical Trial.
Evaluation of the implementation of the One Health approach in Guinea: Application of the NEOH framework to decentralized One Health platforms.
Bongono EF, Hounmenou CG, Maltais S, Mbaye A, Koniono GL, Bangoura ST, Yambayamba M, Diaby M, Keita AK, Touré A, Camara A, Sidimé Y, Rüegg S. Bongono EF, et al. One Health. 2026 Apr 24;22:101428. doi: 10.1016/j.onehlt.2026.101428. eCollection 2026 Jun. One Health. 2026. PMID: 42111337 Free PMC article.
The One Health Index (OHI) and the One Health Ratio (OHR) were calculated to assess overall integration and internal balance between operational and support components, respectively. ...In contrast, Boke, Kindia, and Mamou exhibited low scores in Sharing, Learning, and Sys …
The One Health Index (OHI) and the One Health Ratio (OHR) were calculated to assess overall integration and internal balance between …
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD. Xu K, et al. Nat Med. 2018 Jun;24(6):857-867. doi: 10.1038/s41591-018-0042-6. Epub 2018 Jun 4. Nat Med. 2018. PMID: 29867235 Free PMC article.