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Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis.
Nakatogawa H, Ishii J, Asai E, Ohsumi Y. Nakatogawa H, et al. Autophagy. 2012 Feb 1;8(2):177-86. doi: 10.4161/auto.8.2.18373. Epub 2012 Feb 1. Autophagy. 2012. PMID: 22240591
Molecular dissection of autophagy: two ubiquitin-like systems.
Ohsumi Y. Ohsumi Y. Nat Rev Mol Cell Biol. 2001 Mar;2(3):211-6. doi: 10.1038/35056522. Nat Rev Mol Cell Biol. 2001. PMID: 11265251 Review.
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway.
Kirisako T, Ichimura Y, Okada H, Kabeya Y, Mizushima N, Yoshimori T, Ohsumi M, Takao T, Noda T, Ohsumi Y. Kirisako T, et al. J Cell Biol. 2000 Oct 16;151(2):263-76. doi: 10.1083/jcb.151.2.263. J Cell Biol. 2000. PMID: 11038174 Free PMC article.
Apg2p functions in autophagosome formation on the perivacuolar structure.
Shintani T, Suzuki K, Kamada Y, Noda T, Ohsumi Y. Shintani T, et al. J Biol Chem. 2001 Aug 10;276(32):30452-60. doi: 10.1074/jbc.M102346200. Epub 2001 May 29. J Biol Chem. 2001. PMID: 11382761
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells.
Mizushima N, Yamamoto A, Hatano M, Kobayashi Y, Kabeya Y, Suzuki K, Tokuhisa T, Ohsumi Y, Yoshimori T. Mizushima N, et al. J Cell Biol. 2001 Feb 19;152(4):657-68. doi: 10.1083/jcb.152.4.657. J Cell Biol. 2001. PMID: 11266458 Free PMC article.
Formation process of autophagosome is traced with Apg8/Aut7p in yeast.
Kirisako T, Baba M, Ishihara N, Miyazawa K, Ohsumi M, Yoshimori T, Noda T, Ohsumi Y. Kirisako T, et al. J Cell Biol. 1999 Oct 18;147(2):435-46. doi: 10.1083/jcb.147.2.435. J Cell Biol. 1999. PMID: 10525546 Free PMC article.
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy.
Tanida I, Mizushima N, Kiyooka M, Ohsumi M, Ueno T, Ohsumi Y, Kominami E. Tanida I, et al. Mol Biol Cell. 1999 May;10(5):1367-79. doi: 10.1091/mbc.10.5.1367. Mol Biol Cell. 1999. PMID: 10233150 Free PMC article.
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