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Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
Ohta S. Ohta S. Methods Enzymol. 2015;555:289-317. doi: 10.1016/bs.mie.2014.11.038. Epub 2015 Jan 21. Methods Enzymol. 2015. PMID: 25747486 Review.
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K. Fu Y, et al. Among authors: ohta s. Neurosci Lett. 2009 Apr 3;453(2):81-5. doi: 10.1016/j.neulet.2009.02.016. Epub 2009 Feb 12. Neurosci Lett. 2009. PMID: 19356598
In Parkinson's disease, mitochondrial dysfunction and the associated oxidative stress are major causes of dopaminergic cell loss in the substantia nigra. ...Our studies suggest that hydrogen water is likely able to retard the development and progression of Parkinson's
In Parkinson's disease, mitochondrial dysfunction and the associated oxidative stress are major causes of dopaminergic cell loss in t …
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
Ohta S. Ohta S. Curr Pharm Des. 2011;17(22):2241-52. doi: 10.2174/138161211797052664. Curr Pharm Des. 2011. PMID: 21736547 Free PMC article. Review.
Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.
Ohta S. Ohta S. Pharmacol Ther. 2014 Oct;144(1):1-11. doi: 10.1016/j.pharmthera.2014.04.006. Epub 2014 Apr 24. Pharmacol Ther. 2014. PMID: 24769081 Review.
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study 1.
Mikami T, Tano K, Lee H, Lee H, Park J, Ohta F, LeBaron TW, Ohta S. Mikami T, et al. Among authors: ohta f, ohta s. Can J Physiol Pharmacol. 2019 Sep;97(9):857-862. doi: 10.1139/cjpp-2019-0059. Epub 2019 Jun 28. Can J Physiol Pharmacol. 2019. PMID: 31251888 Clinical Trial.
Endurance and fatigue were significantly improved in the H(2) group as judged by maximal oxygen consumption and Borg's scale, respectively. ...
Endurance and fatigue were significantly improved in the H(2) group as judged by maximal oxygen consumption and Borg's scale, respect …
Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.
Iuchi K, Nishimaki K, Kamimura N, Ohta S. Iuchi K, et al. Among authors: ohta s. Can J Physiol Pharmacol. 2019 Oct;97(10):999-1005. doi: 10.1139/cjpp-2018-0741. Epub 2019 Jul 11. Can J Physiol Pharmacol. 2019. PMID: 31295412
Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
Nishimaki K, Asada T, Ohsawa I, Nakajima E, Ikejima C, Yokota T, Kamimura N, Ohta S. Nishimaki K, et al. Among authors: ohta s. Curr Alzheimer Res. 2018 Mar 14;15(5):482-492. doi: 10.2174/1567205014666171106145017. Curr Alzheimer Res. 2018. PMID: 29110615 Free PMC article. Clinical Trial.
For a randomized double-blind placebo-controlled clinical study, 73 subjects with MCI drank ~300 mL of H2-water (H2-group) or placebo water (control group) per day, and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) scores were determined after 1 ye …
For a randomized double-blind placebo-controlled clinical study, 73 subjects with MCI drank ~300 mL of H2-water (H2-group) or placebo water …
Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
Iuchi K, Imoto A, Kamimura N, Nishimaki K, Ichimiya H, Yokota T, Ohta S. Iuchi K, et al. Among authors: ohta s. Sci Rep. 2016 Jan 7;6:18971. doi: 10.1038/srep18971. Sci Rep. 2016. PMID: 26739257 Free PMC article.
The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research.
Ohta S, Nakao A, Ohno K. Ohta S, et al. Med Gas Res. 2011 Jun 7;1(1):10. doi: 10.1186/2045-9912-1-10. Med Gas Res. 2011. PMID: 22146082 Free PMC article.
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Terasaki Y, Ohsawa I, Terasaki M, Takahashi M, Kunugi S, Dedong K, Urushiyama H, Amenomori S, Kaneko-Togashi M, Kuwahara N, Ishikawa A, Kamimura N, Ohta S, Fukuda Y. Terasaki Y, et al. Among authors: ohta s. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L415-26. doi: 10.1152/ajplung.00008.2011. Epub 2011 Jul 15. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21764987
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